직업적 급혈자의 빈혈에 관한 연구(제1보)
An Anemia Study on Professional Blood Donors(Report 1)

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서울대학교 의과대학
Seoul J Med 1961;2(1):39-49
The various hematological examinations on one
hundred and fifty- three male donors. thirty five
female donors and thirty donors with severe anemia
who visited the Seoul National University Hospital
Blood Bank and the National Blood Bank were carried
out and the results are as follows:
1. In the majority of prefessional donors, who
had donated blood even once a year, the
values of hemoglobin, hematocrit and erythrocytes
were decreased. The diversity from norma
values became greater as the frequency of donation
2. The whole blood specific gravity was lower as
the frequency of donation increased, while the
specific gravity of the plasma was almost unchanged.
3. The diminution of serum iron in the donors was
most remarkable and appeared early while the
anemia was only slight. The serum copper levels
remained within normal limits.
4. The total serum proteins were not altered in cases
of infrequent donation, but were decreased
as the frequency of donation occurred.
5. Applying the pyrogen test to the donors, the
hemopoietic function of the white blood corpuscle
series in the bone marrow was found to be similar
to that of the normal.
6. Bone marrow examination of the donors revealed
the hemopoietic function to be normal, with
hyperactivity present in the erythrocytic series.
7. The oral iron loading test demonstrated that
iron was readily absorbed and that the anemia
of the donors improved gradually with the
administration of iron preparations.
8. The total acidity of the gastric juice of the donors
with severe anemia due to repeated donations
was lower than normal.
9. A remarkable decrease of serum iron as well as
an increased unsaturated iron binding capacity in
serum were observed in the professional donors.
10. The iron-deficient, microcytic and hypochromic
anemia was provoked In almost all cases of the
professional donors, unless bleeding was limited
to three times a year in the male donors and to
two times a year in the female donors.
11. In the female donors, the decrease of all hematological
values were more marked and the
anemia was provoked earlier than in the male
ia The author concludes that frequent blood donations
should be avoided and that all prefessional
donors should be given supplemental iron as a
deficiency in this mineral is demonstrable in
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 02 No.1 (1961)
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