한국인의 간경변증에 관한 부검통계

Abstract

Although liver cirrhosis has been recognized as a relatively common disease in Korea there have been almost no statistical reports concerning cirrhosis. I present here a statistical study of liver cirrhosis from 1990 autopsies. performed in a period of seventeen years(1929~19B, 1954~1957) in the Department of Pathology, College of Medicine, Seoul National University. In this study the classification of liver cirrhosis depended upon the diagnosis noted on the autopsy protocol. 1. Incidence and types: There were eighty-five cases of cirrhosis of liver(male seventy-one cases femalefourteen cases), accounting for 7.79% of all auto-psied cases. The types of liver cirrhosis, which were recognized in this study, were as follows; Laennec's liver cirrhosis, forty-two cases(male thirty-eight cases, female four cases), biliary liver cirrhosis, six cases (male five cases, female one case), cardiac liver cirrhosis. fourteen casesr male nine cases, female five cases), parasitic liver cirrhosis, ten cases(male ten cases), Morbus Banti, twelve cases/male eight cases, female four cases), undetermined type, one case(male one case). 2. From the chronological standpoint there was an increase in incidence of cirrhosis in recent years. 3. There was an increase in incidence after the third decade, with the peak in the fifth decade. Diagrams of the incidence of types of liver cirrhosis in the various age groups are shown. 4. The incidence among females has increased in recent years. 5. Studies concerning jaundice, ascites, weights of liver and spleen, and other pathologic anatomical findings in the types of cirrhosis of the liver were made. 6. It has found that the blood pressures of patients with liver cirrhosis but without renal disease were generally low. Not only were the average blood pressures of such patients below hypertensive levels (Master etal) but they were actually lower than average normal blood pressures in healthy individuals( Symonds). On the other hand, in this series there were four cases of cirrhosis associated with renal disease, of these cases, one had moderate hypertension, one had minimal hypertension, one had normal blood pressure and one had hypotension (Symonds). 7. There were seven cases of cirrhosis of liver with hepatom(8. 23% of all liver cirrhosis cases).and four cases of Laennec's cirrhosis with hepatom 9.5% of all Laennec's cirrhosis cases. 8. The clinical diagnosis was madeaccurately III about one half of the cases in which liver cirrhosis was ascertained in autopsiesas a chief or an accessory finding.