조직비반세포의 출현 분포에 관한 연구
Studies on Occurence and Distribution of Tissue Mast Cells

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서울대학교 의과대학
Seoul J Med 1961;2(2):35-72
The morphology, distribution and stainability of tissue
mast cells were studied from the tissues taken from
selected portions of various organs of the following
adult animals; xr«, pig, rabbit. guinea-pig, albino-rat,
mouse, fowl, sparrow and frog. And particularly albino
rats were selected by different ages 03! gestation day
l6-!- g.d., l8t g.d., 19t g.d., 20t g.d., 2It g.d., at birth.
24hrs., Sd, 5d, lad, lfid, 20d, l m, 3m, Gm) and sexes.
The following conclusions were made.
1) Tissue mast cells were observed in each species
of animals. The density of mast cell population in
various organs of various species of animals has shown
a sign-ificant difference according to species of animals.
It was found that the density of mast cell population
is most numerous in cow. pig and dog, being fewer in
fowl, guinea-pig, frog and albino rat in the given order,
and rarest in rabbit, mouse and sparrow.
Numerous tissue mast cells were observed in skin,
tongue, lung and gastrointestinal tract of the above
animals examined. However, they were absent or
relatively few in kidney, pancreas and brain tissues.
Histological potrions in which tissue mast cells are
abundantly found are a little different according to
species of animals. However, they are generally
consistant in the organ.
The most numerous mast cells were found in the
hepatic capsule of cow among the all specimens
Tissue mast cells were distributed numerously in
connective tissue especially in around blood vessels
and gland ducts. However. the density of mast cell
population was not always parallel to the amount
of connective tissues.
The location and arrangement of tissue mast cells
in various organs of various species of animals seem
to be somewhat peculiar to each species of animals.
2) The form of tissue mast cells of various species
of animals was found to be multifarious. It was usually
round and ovoid. however the spindle, long. irregular
and spined forms were also observed. It seemed to
show some difference according to histological portions.
Nuclei of tissue mast cells generally correspond to
the form of cells and they are uninucleate and situated
in central or eccentric portions of cells and commonly
stained faintly.
Granules of tissue mast cells are usually round,
uniform and are mostly compact in their cytoplasm.
3) Tissue mast cells stain red-purplish, purple-bluish
or dark purple-bluish, but mostly red-purplish in toluidine
blue stain by Rasanen formula. The stainability
was mostly distinct.
4) In albino rats. the density of mast cell population
in various organs is definitely related with the age
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 02 No.2 (1961)
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