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Risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in Japanese quail .
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seok, Seung-Hyeok | - |
dc.contributor.author | Park, Jong-Hwan | - |
dc.contributor.author | Cho, Sun-A. | - |
dc.contributor.author | Kim, Dong-Jae | - |
dc.contributor.author | Bae, Bo-Kyoung | - |
dc.contributor.author | Park, Jae Hak | - |
dc.date.accessioned | 2009-08-31T23:49:21Z | - |
dc.date.available | 2009-08-31T23:49:21Z | - |
dc.date.issued | 2007-07-16 | - |
dc.identifier.citation | Ecotoxicol. Environ. Saf. 71, 245-251 | en |
dc.identifier.issn | 0147-6513 | - |
dc.identifier.uri | https://hdl.handle.net/10371/8307 | - |
dc.description.abstract | Six-week-old male and female Japanese quails (Coturnix japonica) received two organophosphate pesticides, isazofos and pyraclofos, for a 21-day dietary toxicity test, based on the OECD workshop report. During the treatment period, body weight and food consumption of the quail decreased with exposure to either isazofos or pyraclofos. Using the up-and-down procedure to determine the 50% mortality value, we found that the 21-day LC50 of isazofos and pyraclofos were 40 and 87 mg/kg body weight, respectively. Ataxia, salivation, diarrhea, ruffled feathers, and convulsions at a dead point were observed with both pesticides. The tips of the villi were necrotic in the high dosage groups of isazofos- and pyraclofos-treated quail. Based on these results, body weight, food consumption, clinical signs, and histopathological findings may be useful parameters for detecting the dietary toxicity associated with isazofos and pyraclofos exposure. In addition, Japanese quail could be an excellent bird model for monitoring the toxicological risks of pesticides in Korea. | en |
dc.description.sponsorship | This study was supported by the Korea Institute of Environmental Science and Technology (KIEST), a Korea Research Foundation Grant (KRF-005-E00077), and additional financial support from the BK21 Program for Veterinary Science. | en |
dc.language.iso | en | - |
dc.publisher | Elsevier | en |
dc.subject | Dietary toxicity | en |
dc.subject | Japanese quail | en |
dc.subject | Isazofos | en |
dc.subject | Pyraclofos | en |
dc.title | Risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in Japanese quail . | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 석승혁 | - |
dc.contributor.AlternativeAuthor | 박종환 | - |
dc.contributor.AlternativeAuthor | 조선아 | - |
dc.contributor.AlternativeAuthor | 김동재 | - |
dc.contributor.AlternativeAuthor | 배보경 | - |
dc.contributor.AlternativeAuthor | 박재학 | - |
dc.identifier.doi | 10.1016/j.ecoenv.2007.05.015 | - |
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