SHERP

장내세균성 풍토병 발생기전에 관한 면역학적 연구
A Study on Specific and Non-specific Aspects of the Immunities to the Enteric Infections

Cited 0 time in webofscience Cited 0 time in scopus
Authors
최성배; 조현숙; 박원철; 이승훈
Issue Date
1973-03-01
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1973;14(1):6-14
Abstract
The Occurrence of infectious disease is not merely
due to contact between microbial agents and host
but rather a kind of results of complex interaction
between microbial agents and resistance mechanisms
of the host.
To cause infectious disease. infectious agents have
to resist and overcome the specific and non specific
defense mechanisms of the host.
Host resistance is determined by both non specific
physiological and morphological factors and specific
factors of immunological phenomena.
In order to investigate specific and non specific
aspects of the immunities to the enteric infections.
the increase of agglutinin titers of serum. the
enhancement of antibacterial activities of serum and
the enhancement of phagocytosis as results of
vaccination were followed.
Results were obtained as follows.
1. The agglutinin titers of immune sera were naturally
highest to the organism used in the preparation
of the vaccines.
However:
a. Agglutinin titers to S. typhi were more or
less higher in the anti-Sh. dysenteriae
and and anti-Es. coli sera than in control
sera.
b. Agglutinin titers to Sh, dysenteriae were
noticiably higher in the anti-So typhi and
anti-Es. coli sera than in control sera.
C. Agglutinin titers to Es. coli were significantly
higher in anti-So -typhi and anti-Sh,
dysenteriae sera than in control sera.
2. The enhancement of antibacterial activities of
immune sera were naturally most noticeable to
the organism used in the preparation of the
vaccines.
However:
a. The enhancement of antibacterial activities
to S. typhi were more noticeable in antiSh.
dysenteriae and anti-Es, coli sera than
in control sera.
b. The enhancement of antibacterial activities
to Sh, dysenteriae were more noticeable in
anti-Es. coli and anti-So typhi sera than in
control sera.
c. The enhancement of antibacterial activities
to Es. coli were more noticeable in ant i-Sh.
dysenteriae sera than in antj-S. typhi
sera or control sera up to 60 minutes.
Thereafter viable units of Es. coli showed
increase in the immune and control sera.
3. The enhancement of phagocytic activities of
immune sera were naturally most significant to
organism used in the preparation of the vaccine.
However:
a. The enhancement of phagocytic activities
to S. typhi were more noticeable in antiSIl.
dysenteriae and anti-Es, coli sera than
in control sera.
b. The enhancement of phagocytic activities
to Sh. dysenteriae were more noticeable in
anti-Es. coli and anti-So typhi sera than
in control sera.
C. The enhancement of phagocytic activities
to Es. coli were more noticeable in antiSh,
dysenteriae and anti-So typhi sera
than in control sera.
Language
Korean
URI
http://hdl.handle.net/10371/8361
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 14 No.1 (1973)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse