Spatial Patterning of Fibroblast Cells with Fabricating Holographic Patterning on the Photoresponsive Polymer

Abstract

Microtopographic feature was obtained by laser holographic fabrication on the photoresponsive polymer. Surface feature was localized using photomask for developing two dimensional cellular pattering. Fibroblast cells were cultured and proliferated only on the patterned substrate. Obtained cellular pattering suggests that the laser fabricating with photoresponsive polymer would be applied to regenerating new tissue and developing biomedical device of living cells.