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Submicron-scale topographical control of cell growth using holographic surface relief grating

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Authors
Baac, Hyoungwon; Lee, Jeong-Hyun; Seo, Jong-Mo; Park, Tai Hyun; Chung, Hum; Lee, Sin-Doo; Kim, Sung June
Issue Date
2004-01
Publisher
Elsevier
Citation
Mater. Sci. Eng., C 24 (2004) 209
Keywords
Topographical controlHolographyCell attachmentCell orientationPhoto-responsive polymerSurface relief grating
Abstract
The cell orientation and attachment were controlled by a submicron-scale topographical cue. For achieving the submicron undulation of
surface topography, the laser holography on a photo-responsive azobenzene copolymer layer has been employed to produce surface relief
grating (SRG) which has a regular sinusoidal shape. Cultured human astrocytes (HA) were preferentially attached onto the SRG surface and
highly elongated along the SRG direction. This topographical control scheme would be very efficient to control the cell growth for cellular
engineering applications and to understand the interactions of the cells with a submicron-scale topographical surface.
ISSN
0928-4931
Language
English
URI
http://hdl.handle.net/10371/8921
DOI
https://doi.org/10.1016/j.msec.2003.09.009
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Journal Papers (저널논문_전기·정보공학부)
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