가토의 체위변동에 따른 혈장 Renin Activity 변화

Abstract

In order to investigate the changes in plasma renin activity at various postures in rabbits, the experi mental animals were maintained at prone, side. upright, and headside down postures for 10 hours. Plasma renin activity was measured by the method of radioimmunoassay. The data obtained were as follows: 1) At prone posture, the plasma renin activity was 14.72±3. 49 nanogram per 100ml plasma per hour. which was regarded as resting plasma renin activity. 2) At side posture, the plasma renin activity was 46.60±5. 41 ng/100ml plasma/hr, which was signi ficantly higher than that of resting plasma renin activity. 3) At upright posture, the plasma renin activity was 45.82±11. 51 ng/100ml plasma/hr, which was also significantly higher than that of resting level 4) At headside down posture, the plasma renin activity was 44. 16±10. 33 ng/1ooml plasma/hr, which Was also significantly higher than that of resting plasma leve l. From the adove results. it was concluded that the postures other than normal prone position in rabbits stimulated the release of renin in the kidney