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trans-1, 4, 5, 6 Tetrahydro-2-(3-hydroxystyryI)-1-methylpyrimidine(CP-14,445)의 Trichocephalus trichiurus에 대한 구충효과 : Anthelminthic effect of trans-1, 4, 5, 6 Tetrahydro-2-(3-hydroxystyryI)-1-methylpyrimidine(CP-14,445) on Trichocephalus trichiurus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Chan Woong | - |
dc.contributor.author | Lim, Jung Kyu | - |
dc.contributor.author | Shim, Sang Jung | - |
dc.contributor.author | Kim, Myung Suk | - |
dc.contributor.author | Jeong, Myung-Hee | - |
dc.date.accessioned | 2009-09-14T04:47:56Z | - |
dc.date.available | 2009-09-14T04:47:56Z | - |
dc.date.issued | 1973-09 | - |
dc.identifier.citation | Seoul J Med, Vol.14 No.3, pp. 228-232 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/9193 | - |
dc.description.abstract | CP-14,445, one of pyrimidine derivative, has been
expected to be a potent antiwhipworm agent for Trichocephalus trichiurus, and its activity in human infestation, its side effect , and safety through pre• liminary trial is the subject of the present study. In 70 case of Trichocephalus trichiurus infestation one single oral dose of 10mg/kg of CP•14.445 as a syrup formulation. produced following results. CP-14.445 showed negative conversion rate of 63% for T. trichiurus but its egg reduction rate at 22nd post-treatment day was 91.5% For the Ascariasis, no effect was observed with one single oral dose of 10mg/kg In all tested cases , one single oral dose of 10 mg/kg of CP-14,445 was well tolerated and there was no detectable objective and/or subjective side effect. Blood chemistry, blood film and urinalysis were taken in all patients and CP-14,445 was so safe as to revel that no difference was observed between pre- and post-treatment with one single oral dose of 10mg/kg of CP-14,445. | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | trans-1, 4, 5, 6 Tetrahydro-2-(3-hydroxystyryI)-1-methylpyrimidine(CP-14,445)의 Trichocephalus trichiurus에 대한 구충효과 | - |
dc.title.alternative | Anthelminthic effect of trans-1, 4, 5, 6 Tetrahydro-2-(3-hydroxystyryI)-1-methylpyrimidine(CP-14,445) on Trichocephalus trichiurus | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 박찬웅 | - |
dc.contributor.AlternativeAuthor | 임정규 | - |
dc.contributor.AlternativeAuthor | 심상정 | - |
dc.contributor.AlternativeAuthor | 김명석 | - |
dc.contributor.AlternativeAuthor | 정명희 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 232 | - |
dc.citation.number | 3 | - |
dc.citation.pages | 228-232 | - |
dc.citation.startpage | 228 | - |
dc.citation.volume | 14 | - |
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