S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 04 No.4 (1963)
견의 뇌혈액순환과 그의 완전분리법
Cerebral Circulation in thε Dog and a Surgical Technique for Isolation of Blood Flow to the Brain
- Issue Date
- 서울대학교 의과대학
- Seoul J Med, Vol.4 No.4, pp. 1-8
- For a number of physiological experiments the
cross circulation technique is extremely useful. It
is essential however, that complete isolation be
achieved. Otherwise, the results obtained are likely
to be misleading. Hence, knowledge of the circulation
to the brain of the dog is a prerequisite to
certain types of study designed to elucidate central
nervous chemo-sensitive regulatory mechanisms.
Many attempts have been made in earlier experiments
to isolate the head from the body circulation.
Except for decapitation experiments, in which the
anemia is total, most other ligation experiments
permitted long survival times, whether by permanent
ligation of both carotid and vertebral arteries3) ,
or by combined ligation of innominate and left
subclavian arteriesJi) . These observations suggest
extensive collateral flow to vital areas of the brain.
The spinal vessels carry an amount of blood
su 며cient to mainain the activity of nerve cells in
the brain for a surprisingly long period6, ll) . BrownZ)
and HofF also have shown that spinal vessels
readily carry dyes to and from the brain.