1971년도 감염성 질환의 임상역학적 연구

Abstract

The developments of appropriate antimicrobial therapy and vaccination have recently brought significant changes on the ecological patterns of microbial diseases of man. It was considered worthwhile to study the recent trends and present status of microbial diseases in this country. Thus the relative incidences and etiological relati onships of bacterial species, the pattern of their distributions on the age and sex , and of drug sensi tivities among the strains were studied for the patients of SNU Hospital from April to December in 1971. The results might be summerized as follows; 1. Most stains of Staphylococcus aureus were pri ncipally isolated from the patients with wound infections, osteomyelitis, pneumonia and abscess, and from pus and throat swabs as clinical specimens. About 83% of strains were more susceptible to the leucomycin than any other antibiotics used. 2. Alpha-hemolytic streptococci were mainly isolated from the patients with pneumonia and bronchitis, and from sputum and throat as clinical specimens. 92% of strains showed the susceptibility to the the penicillin and the leucomycin , respectively. 3. High frequencies of the isolation of Diplococcus pηeμ mon iae were showed in the patients with pneu monia and bronchitis, and in such clinical specimens as sputum and throat swab. The susceptible strains to the penicillin and the chloramphenicol amounted to 97% and 90%, respectively. 4. The strains of Escherichia coli were isolated almost from the patients with urinary tract infection , and mostly from urine and pus in the clinical specimens. 62% of the strains were not only susceptible to the neomycin but also 59% to the kanam YCll1. 5. The isolated strains of Coliform bacilli were closely related to the patients with wound infection and urinary tract infection , and to such clinical specimens as urine and pus. Frequencies of the susceptible strain to the kanamycin and the neomycin showed 72% and 62%, respectively. 6. High incidences of Pseudomonae aerμ:ogmosa isolated were showed in the patients with wound infection, abscess, pneumonia, urinary tract infection and burn , and in clinical specimens such as pus , sputum and urine. 56% of the strains were susceptible only to the colimycin. 7. Shigella group B were isolated only from the patients with dysentery and diarrhea and mostly from rectal swab in clinical specimens. 82% of the strains were susceptible to the kanamycin , and also 74% to the neomycin. 8. Most strains of Salmoηella group D were isolated only from the patients with F. U. O. and typhoid fever , and in the clinical specimens from blood and rectal swab. AIl of the strains isolated were susceptible to the neomycin but only 75% to the chloramphenicol. 9. The isolated strains of Klebsiella aerogenes were closely related to the patients with urinary tract infection, wound infection, pneumonia and abscess and in the isolating specimens to urine , pus , sputurn and throat swab. No more than 40% of the strains were susceptible to both the kanamycin and neomyc ll1. 10. Significant conclusions can not be derived from the distibution patterns of the isolated bacterial species on the age and sex in this report.