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Thalamofrontal Circuitry Abnormalities and Frontal Executive Dysfunction in Juvenile Myoclonicepilepsy : Diffusion Tensor MRI and Neuropsychological Studies

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Authors
Kim, Ji Hyun; Kim, J. H.; Suh, S. I.; Seol, H. Y.; Jung, Ki-Young; Koh, S. B.
Issue Date
2009-11
Publisher
Wiley
Citation
Epilepsia, Vol.50 Suppl.11, p. 81
Keywords
의약학
Abstract
Rationale: Visual assessment of structural MRI is, by definition, normal
in patients with juvenile myoclonic epilepsy (JME), a major subsyndrome
of idiopathic generalized epilepsy. However, recent quantitative
MRI studies have shown structural abnormalities in frontal and thalamic
grey matter (GM) in JME. In the present study, we addressed the issue of
whether diffusion tensor MRI (DTI) can detect white matter abnormalities
in patients with JME. We also performed several neuropsychological
tests to evaluate frontal lobe dysfunctions in JME patients as compared to
control subjects.
ISSN
0013-9580
Language
English
URI
http://hdl.handle.net/10371/92644
DOI
https://doi.org/10.1111/j.1528-1167.2009.02377.x
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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