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College of Medicine/School of Medicine (의과대학/대학원)
Dermatology (피부과학전공)
Journal Papers (저널논문_피부과학전공)
Penicillamine-induced elastosis perforans serpiginosa and cutis laxa in a patient with Wilson's disease
- Issue Date
- 2010-11
- Publisher
- Korean Dermatological Association
- Citation
- Annals of Dermatology, Vol.22 No.4, pp. 468-471
- Keywords
- 복합학 ; Cutis laxa ; Elastosis perforans serpiginosa ; Penicillamine ; Wilson’s disease
- Abstract
- Elastosis perforans serpiginosa (EPS) is a rare reactive perforating dermatosis that is characterized by the transepidermal elimination of abnormal elastic fibers. Penicillamine, which is one of the clear triggers for EPS, is a heavy metal chelator that is primarily used for disorders such as cystinuria and Wilson's disease. It may cause alterations in the dermal elastic tissue such as pseudo-pseudoxanthoma elasticum, acquired cutis laxa, EPS and anetoderma. Herein we present a case of cutis laxa and EPS in a 34-year-old man who was previously on a long-term, high-dose of penicillamine for Wilson's disease. The combination of EPS and cutis laxa induced by penicillamine has rarely been reported and we report the first such case in Korea.
- ISSN
- 1013-9087
- Language
- English
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