Publications
Detailed Information
칼슘, 란타늄, 망간 이온이 토끼 유두근 완만내향전류 및 수축에 미치는 영향 : Effect of Calcium, Lanthanum and Manganese ions on the Slow Inward Current and Contraction in the potassium depolarized rabbit papillary muscle
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 엄융의 | - |
dc.date.accessioned | 2009-09-15T14:02:25Z | - |
dc.date.available | 2009-09-15T14:02:25Z | - |
dc.date.issued | 1978-03 | - |
dc.identifier.citation | Seoul J Med, Vol.19 No.1, pp. 15-23 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/9345 | - |
dc.description.abstract | The effects of Ca++, La+++ and )\'In++ on the elecmuscletrical
and mechanical responses of papillary muscle partially depolarized by 27 mM K十were studied in rabbits. 1. When resting membrane potential of partially depolarized papillary muscle was set at • 40 to -45 mY. therewere no electrical and mechanical activities, after 10μM histamine addition , however , they reappeared. 2. After addition of histamine, Ca++ increased the amplitude of action potential, ψmax (maximum rate of depolarization, (dY/dt)max) and magnitude of contraction. the duration of action potential, however , was shortened. 3. La+++ in concentration of 10-100 I'M decreased the amplitude of action potential from control value of 77±1. 0 mY to 49±1. 0 mY (Mean±S.E.) , Vmu and magnitude of contraction up to 21. 9±3. 1% and 38. 3±2. 4% of control respectively. The duration of action potential was shortened from 245±18.3 msec of control to 150±14.7msec. 4. Mn++(30-300pM) decreased the amplitude of action potential from 75±1. 3 mY to 59. 7±0. 9 mY, Vmo. and magnitude of contraction up to 61. 4±1O. 9 % and 75. 7±3. 0% of control , but lengthened the duration slightly 5. The above results suggest that the amplitude of action potential and ψm o. of partially depolarizcd papillary muscle are a measure of calcium-dependent slow inward current or calcium conductance. gCa. | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | 칼슘, 란타늄, 망간 이온이 토끼 유두근 완만내향전류 및 수축에 미치는 영향 | - |
dc.title.alternative | Effect of Calcium, Lanthanum and Manganese ions on the Slow Inward Current and Contraction in the potassium depolarized rabbit papillary muscle | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Earm, Yung E | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 23 | - |
dc.citation.number | 1 | - |
dc.citation.pages | 15-23 | - |
dc.citation.startpage | 15 | - |
dc.citation.volume | 19 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.