간경변증환자의 복수량 간접측정

Abstract

This study usinig the indirect dilution method employing bromsulfalein was undertaken to measure ascitic fluid volumes of patients who had the classical manifestations of portal cirrhosis with ascites. In addition, the investigation was designed to compare the results of the indirect method with that of the direct method of paracentesis. The bromsulfalein dilution method described by Baker, et aI. , was followed: A sample of ascitic fluid approximately equal to the volume of bromsulfalein to be injected, was withdrawn through a 20-gauge needle. Five millimeters of 5 % B.S,P, solution was injected through the same needle. After injection, the needle was withdrawn, the abdomen was ballotted, and the pati~nts position shifted frequently during a 15 minute period. A 20-gauge needle was then inserted intraperitonealy at a site 15 to 20em. away from the site of the previous injection. and ascitic fluid samples were periodically withdrawn. Following the indirect measurement of ascitic fluid volume in 7 patients, paracentesis were performed to obtain a direct measurement of the ascitc fluid volumes. The results are summarized as follows. 1) No toxic or side reactions were noted after intraperitoneal injection of B.S.P. solut'on. 2) The mean value of ascitic fluid volumes by indirect measurement in the 12 cases is 8, 533 millilters, and in 7 of these patients, the mean volume by direct measurement is 7,990 milliliters. It can be seen that the two volumes compare favorablo with a mean difference of 420 milliliters. 2) FOr routine clinical purposes, B.S.P. may be used to estimate ascitic fluid volumes of liver cirrhosis by the indirect dilutbn method.