비소제의 백일해균 발육억제에 관한 연구

Abstract

Authors investigated bacteriostatic effect of arsenic· als such as arsenious acid, osvarsan, neoarsphenamine, mapharsen to H.pertussis and simultaneously to Staph. aureus, E. coli, Pseudo. pyocyanea , Sh. dysetenriae and S. typhi and following results were obtained. 1) Trivalent inorganic arsenic , arseious acid was ba· cteriostatic even in the concentration of O. 01%dilution to H. Pertussis and the effect of trivalent erganic ars· enicals, neoarsphenamine and mapharsen was comparable to that. Whereas, pentavalent organic arsenicals, carbarsone and osvarsan was muchless effective as compared with them. 2) Generally , H. pertussis was most sensitive to the arsenicals, next to this was S. typhi. 3) P. pyocyanea was least sensitive to arsenicals. Staphylococcus and other enteric group had place between H. pertussis and P. pyocyanea in their sensiti· vity to the arsenicals.