SHERP

혈장 수소이온 농도와 심장박출량
Cardiac Output During the Metabolic Acid-Base Disturbance in the Rabbit

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Authors
이재성; 김우겸
Issue Date
1975-09
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1975;16(3):193-200
Abstract
Cardiac output and hemodynamics were determ i n e d in the rabbit during the acute acid-base disturbance of metabolic origin by the intravenousi n fu si o n of 0.3 N hydrochloric acid or 0.6 M/L
sodium bicarbonate solution. Cardiac output was measured analyzing the saline
dilution curve recorded on physiograph the extra•
ml/min/ aterial conductivity, using Stewart-Hamilton form•
(± ula.
Under each level of plasma hydrogen ion concen
tration , arterial blood pressure, heart rate, cardiac
index, stroke volume and total peripheral resistance
were measured and relation of them were analyzed
1 . Normal cardiac index measured by saline cond
uctivity method in the rabbit was 72 C±5. 0) mJ!
min/kg. After the infusion of hydrochloric acid,
associated with the decrease of pH from 7.40 of
normal to 7.23 , cardiac index decreased to 50'
0.72 (±4.3) ml/min/kg. During metabolic acidosis,
th e higher the concentration of hydrogen ion ,
the more significantly decreased the cardiac
dex. After the infusion of sodium bicarbonate,
however, associated with the increase of pH from
7.40 to 7.51. cardiac output did not change
significantly.
Language
Korean
URI
http://hdl.handle.net/10371/9436
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 16 No.3 (1975)
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