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한국에 있어서의 정상인과 기관지 천식환자의 혈청 총 IgE치에 관한 연구
Serum Ig E Level in Koreal Sound Controls and Bronchial Asthmatics

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Authors
강석영; 문희범; 홍원선
Issue Date
1981-03
Publisher
서울대학교 의과대학
Citation
Seoul J Med, Vol.22 No.1, pp. 92-97
Abstract
Total serum IgE level were determined in 83
Korean sound controls (male 38, female 45) and 250
bronchial asthmatics (male 136, female 114) who had
not been treated with hyposensitization. The patients
were divided into two small groups, i. e. group (a)
with asthma only and group (b) with other coexistent
atopic diseases.
IgE in serum was measured by the radioimmunosorbent
technique using the kits of Phadebas~ and
following results were obtained.
1. In both control and asthma group, the frequency
distributions of the serum IgE levels were continuous ut not normal.
2. In control group, the serum IgE levels ranged
from 8 to 475 I.U./ml and the mean and the standard
deviation was 151±1l4 I.U./ml (male 151±124, female
152±105). There were no differences between sexes
or age groups
3. In patients group, the serum levels ranged from
33 to 7,200 I.U./ml and the mean and S.D. were 1401
±1412I.U./ml (male 1682±1420, female 1073±1217).
The levels of male patients were higher than those
of females. but the reasons were uncertain.
4. No significant differences were found between
the serum IgE levels in group(a) and those in group
(b).
5. The serum IgE level higher than 400I. U./ml was
thought to be significantly raised and such levels were
found in 4.8% of sound controls and in 74% of total
asthma patients. In the laller, the allergic bases may
play major roles in the pathogenesis of the disease
G. Significantly raised serum IgE levels were found
in 93% of the asthma patients under 10 years of age,
indicating the high prevalence of allergic asthma in
childhood.
ISSN
0582-6802
Language
Korean
URI
http://hdl.handle.net/10371/9480
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 22 No.1 (1981)
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