SHERP

항경제의 혈중농도와 부작용에 관한 연구
A correlation study of the appearances of side effects and serum concentrations of anticonvulsant

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Authors
이상복
Issue Date
1981-03
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1981;22(1):98-100
Abstract
In thc 139 epileptic patients attcnding the neurologic department of SNUH in last half year , appearances of
the side effects of diphenylhydantoin (DPH) were
observed in relation to its serum concentrations. They
had taken DPH as only anticonvulsant. Among side
effects of DPH, diplopia, nausea nystagmas were
appeared at the serum conentration of 13~5I'g/ml and
18.0 I'g/ml respectively, which belong to the optimal
therapeutic serum conentration of DPH. Other side
effects, sueh as vomiting, ataxia , dysdiadochokinesis,
dizziness and G- I disturhances were observed all
over the 30pg/m!. There are no difference of sex in
the relation to the dosage and serum conentration
but , there shows the tendencies to take more drugs to
maintain the optimal therapeutic serum concentratIOn
as young the age group of patients.
The related literature were briefly reviewed
Language
Korean
URI
http://hdl.handle.net/10371/9481
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 22 No.1 (1981)
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