Guillain-Barre syndrome 환자의 진단과 근전도소견

Abstract

Electrodiagnostic study-nerve conduction study and electromyography-play an important role in diagnosis and possibly in predicting prognosis of Guillian-Barre Syndrome In the present series , median , ulnar, tibial and peroneal nerves were studied elcctrodiagnostically in 24 patients ranging from 2 to 73 years of age (17 males and 7 females). The results are summarized as follows: 1. Mean motor nerve distal latency was 3.~:ι0 ，9 Insec in median , 3. 3±1. 8 msec in ulnar, 5. 4:::r:. 1. 7 msec in peroneal, and 5. 4±1. 7 msec in tibial nerve• all within normal range, Delayed distal latency in one or more nerves was observed in G cases and 110 response In one or more nerves in 11 cases 2. Motor conduction velocity was 49. 8±~. ~ Mltec in median, 50. 2±1l. ~ Mlsec in ulnar, 42. 7±~. ~ Mlsec in peroneal, and 57. 00±5. 7 Mlsec in tibial statically slowed compared to normal pouplation. 3. Distal latency of SNAP was 2. 7±O. 5 msec in median , 2. 4±O. 6 msec in ulnar 2.5士0.7 mscc in sup. peroneal; and 2. 3±O. 6 msec in sural nerve~all within normal limi t. 4. Amplitude of SNAP is 36.1±15. OmV in median , 39. 6±16. 2mV in ulnar, 15. 6±5. 9mV in sup. peroneal and 29. 8±19.8mV in sural nerves-all within normal limi t. Amplitude was below normal in one or more neves in 5 cases and totally absent in one or morc nerves in 6 cases. 5. There was no significant relation between the elevated protain in CSF and MCV. 6. MCV of median nerve was significantly lower in patient within 3 weeks of onset than after 3 weeks. 7. Fibrillation potential was seen in 19 cases, positive sharp wave in 21 cases, increased insertional activity in 11 cases, polyphasic in 8 cases, decreased or absent motor unit potential in 21 cases.