원발성 골종양의 병리 조직학적 검색

Abstract

A total of 182 cases of primary tumors of bone and cartilage was obtained from the Pathology file of the Department of Pathology, College of Medicine, Seoul National University during a period of 10 years beginning from January 1968 to December 1977. These tumors consisted of 85 cases(47%) of benign tumors and 97 cases(53%) of malignant tumors. Osteo· chondroma was most frequent benign tumor(38. 8%) , followed by giant cell tumor(22.9%) , chondroma (12. 9%) , and osteoid osteoma(9. 4%). Osteosarcoma was the most frequent malignant tumor(49.5%) , followed by myeloma (19. 6%), chondrosarcoma (10.3 %), Ewings tumor(7. 2%) , and fibrosarcoma(7. 2%). Benign tumors were most prevalent in the 2nd and 3rd decade (71. 1%). Osteosarcoma and Ewings tumor were frequent in 2nd decade but chondrosarcoma, myeloma , parosteal osteosarcoma, and chordoma were primarily tumors of adulthood after 40 years of age The long tubular bones including femur and tibia were the site of predilection of benign tumors and osteosarcoma. But enchondroma characteristically involved phalangeal bones of hand. Chondrosarcoma had predilection for innominate bone, sacrum and femur. The chief complaints of bone tumor patient were palpable mass and/ or pain. The duration of symptoms prior to admission was longer in benign tumors in contrast to shorter history in malignant tumors. but a history of 5 years or longer was not unusual in chondrosarcoma and parosteal osteosarcoma