SHERP

연층 백혈구 응집반응의 기전
The Mechanism of Buffy Coat Leukocyte Aggregation Reaction

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Authors
장우현
Issue Date
1981-06
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1981;22(2):221-227
Abstract
aggregation
(BCLA) reaction was the simple and sensitive
test for cell-mediated immunity. Thereafter, some
clinical approaches were performed by several investigators.
However the mechanism of human BCLA
reaction was not studied in detail , This study was
designed to clarify some factors involved in the
mechanism of BCLA reaction and results are summarized
as follows.
1. The strong correlation was observed between
minimal amounts of PPD required for BCLA reaction
and skin indura tion diameter of tuberculin reaction
(correlation coefficiency=-0.648, p<0.005))
2. Optimal temperature of BCLA reaction was
37'C and reaction time was 4 to 6 hours
3. Calcium ion was essential for BCLA reaction
4. Cellular composition of aggregates was mostly of
polymorphonuclear leukocytes and partly of Iymphocytes
and monocytes.
5. BCLA reaction appeared to be mediated by
solublefactor released from sensitized lymphocyte.
Language
Korean
URI
http://hdl.handle.net/10371/9496
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 22 No.2 (1981)
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