미세혈관 문합부위의 병리조직학적 관찰

Abstract

Histopathological features of the anastomotic vessels were studied after microsurgical anastomoses in the femoral vessels of 40 rats. The observation performed under light and electron microspes were summarized as follows 1. Endothelial linings were absent at the anastom 。ti c sites and adjacent regions although the internal elastic membranes remained intact below the missing intimal layer. No endothelial recovery was seen during the 2-week follow-up period in this study. 2. The anastomotic vessels suffered some degree of medial necrosis, and it occured usually along the cut vessel edge or around the suture of the anastomotic sites. The necrotic area consisted of the bulk of degenerating smooth muscle cells with a few of macrophages and fibroblasts, and it was then replaced by collagenous fibers and fibroblasts. 3. Incorrect apposition of the cut vessel edge were often associated with the mural thrombus. Repair then with organization occured by the ingrowth of small capillary loops from the vessel wall, and recanalization commenced