한국인 태아의 대뇌피질 발육에 관한 형태학적 연구

Abstract

An understanding of the development of the cerebra! cortex is essential for an understanding of abnormal conditions in neonates. All of the insults that affect the nervous system of the fetus exert a wide variety of disturbances of neural development that are flagr antly apparent in the neonatal period. There is strong likelihood that many of these insults exert deleterious and far·reaching effects on certain aspects of cerebraI cortical development because cerebral cortex is developing in many distinctive ways and at a very rapid rate. To evaluate the development of cerebral cortex , a total of 86 brains of Korean fetuses of gestational ages ranging from 11 to 40 weeks, was studied The fetuses were products of therapeutic abortions, and were proved to be normal after complete examinatien of fetuses and placentas. The brains were removed as soon as possible after delivery, and were fixed in 10% formalin for 1 to 2 weeks before being examined for this study. Representative blocks were taken from five different portions of cerebrum. Through routine histological process, slides were made and stained with Hematoxylin-Eosin and LuxolFast- Blue for general morphology_ Tables were made to list developmental process of cerebral cortex. And the listing was based on microscopically demonstrated findings and measures of various portions of cerebral cortex.