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Stepwise self-assembly of a protein nanoarray from a nanoimprinted poly(ethylene glycol) hydrogel

Cited 30 time in Web of Science Cited 29 time in Scopus
Authors
Lee, Bong Kuk; Lee, Hae Yeon; Kim, Pilnam; Suh, Kahp Y.; Seo, Jeong Hyun; Cha, Hyung Joon; Kawai, Tomoji
Issue Date
2008-03
Publisher
Wiley-Blackwell
Citation
Small 2008, 4, 342
Keywords
arrayshydrogelsnanolithographyproteinsself-assembly
Abstract
Ultraviolet nanoimprint lithography is used to fabricate nanopatterns of poly(ethylene glycol) (PEG) hydrogel on gold substrates for the construction of protein nanoarrays. A protein nanoarray with a minimum feature size of 100 nm is constructed in the nanowell of the PEG hydrogel by self-assembly with a biotinylated PEG-disulfide, streptavidin, and biotinylated antibody, sequentially (see figure), and confirmed by varying the nanowell height between each step in both solution and air.
ISSN
1613-6810
Language
English
URI
http://hdl.handle.net/10371/9560
DOI
https://doi.org/10.1002/smll.200700865
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Mechanical Aerospace Engineering (기계항공공학부)Journal Papers (저널논문_기계항공공학부)
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