담관계 결석 관련요인에 관한 연구
A Study on Some Risk Factors to Biliary Calculi

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이승규; 안윤옥
Issue Date
서울대학교 의과대학
Seoul J Med 1984;25(2):147-155
Though stones in biliary tree are the common
disease in Korea, known as “stomachache or chestache"
for laymen, reliable morbidity have not been reported
until recently.
Most of biliary calculi could be cured only by
means of surgical modality, If some re asonable risk
factors could be found and effective preventive measures
available, those will be of great value to the
improvement of health and lessening the patient’s
financial burden.
The mechanism of biliary calculi formation is still
not known exactly but the pattern of disease seems
to be influenced not only by geographical location
but also by living habits. For example, with respect
to location of calculi, in contrast to the fact that
gallbladder stone presents more than 9096 of total biliary calculi cases in America and Europe, gallbladder
stone is estimated to be less than 50% of cases
in Korea. Instead, common bile duct and intrahepatic
stone accounts for 40% to 70% of total cases
So the risk factors related to biliary calculi in
Korea might be different to that in America and
Europe, and some attributes such as living habits
and environment may play important roles to gallst~
。n e disease
Therefore, as an initial attempt to figure out the
factors to gallstone in Korea , a case'control study
on risk factors is conducted with 121 cases of
gallstone and 205 cases of control patients
Comparison of some selected attributes such as
sex, age, body weight and height, educational back
ground,socioeconomic status, and clinical laboratory
findings as serum cholesterol, blood hemoglobin, serurn
protein, fasting blood sugar, is made between
case group by the location of stones and control
group patients. Also, chemical analyses of the stones
obtained from 30 cases out of 121 stone pat:ents were
carried out using gas chromatography. And the res
ults of chemical analyses were compared according to
the location.
The results and findings obtained in this study
suggest that the dietary habit certainly is one of the
causal factors of biliary calculi. The diet related to
obesity and diabetes is more prone to cause gall~
bladder stones compared to common bile duct and
intrahepatic stones which are probably provoked by
lowcalory and low protein constitution
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 25 No.2 (1984)
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