한국에 있어서의 알레르기질환의 역학적, 면역학적, 임상적 동태
Epidemiological, Immunological, and Clinical Profiles of Allergic Disea ses in Korea

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강석영; 김유형; 민경업; 문희범; 최병휘
Issue Date
서울대학교 의과대학
Seoul J Med 1984;25(3):277-292
The epidemiological, immunological, and clinical
features were analized in allergic patients visiting
the allergy clinic of Seoul National University Hos·
pital during last 5 years. 75.9% of the patients had
respiratory allergies, 10.1% had cutaneous allergies.
11. 2% had both respiratory and cutaneous allergies.
and 2.8% had anaphylaxis or allergies of other
organs. Classifying respiratory allergies into intrinsic
and extrinsic allergies by disease history and skin
reaction to inhalant allergens, the former constituted
49.6% and the latter 50.4% (perennial, 46.6%,
seasonal, 3.8%)
The mean age of the patients with extrinsic res~
piratory allergies was lower than that of those with
intrinsic allergies especially in males. There were
atopic family histories in 23.5% of total patients
Serum total IgE levels were increased in 68% of
patients with extrinsic respiratory allergies, in 39%
of those with intrinsic respiratory allergies, and in
50% of those with cutaneous allergies
The inhalant allergens showing the most frequent
positive skin reaction were those of house dust mites
and house dus t. Other common allergens included
those of cockroach, hay dust , cat , etc. However skin
reactions to some allergens were not correlated with
disease histories. Allergies to pollens or molds did
not exceed 3% of the causes of rhinitis or asthma.
Food allergens such as buckwheat and pupa seemed
unique in Korea.
The air-borne pollen survey in Seoul area revealed
that the tree season was from mid-March to late·
June, the grass season from late-March to late·Octover,
and the weed season from Mid·June to late-November.
Immunotherapy has been performed in more than
600 patients with respiratory allergies. Besides sym
ptornatic improvement, most patients became less
sensitive in skin test to offending allergens. The skin
test reactivity may be an objective parameter indio
eating the efficacy of immunotherapy during the
maintenance course
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 25 No.3 (1984)
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