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Showing results 1 to 60 of 115

Issue Date	Title / Author(s) / Citation	File
2002	Induction of cyclooxygenase-2 in ras-transformed human mammary epithelial cells undergoing apoptosis Na, Hye-Kyung; Surh, Young-Joon Annals of the New York Academy of Sciences, Vol.973, pp.153-160	DOI
2003-10	Peroxisome proliferator-activated receptor γ (PPAR γ) ligands as bifunctional regulators of cell proliferation Na, Hye-Kyung; Surh, Young-Joon Biochemical Pharmacology, Vol.66 No.8, pp.1381-1391	DOI
2003-11	Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells Kundu, Joydeb Kumar; Na, Hye-Kyung; Chun, Kyung-Soo; Kim, Young-Kyung; Lee, Sang Jun; Lee, Sang Sup; Lee, Ok-Sub; Sim, Young-Chul; Surh, Young-Joon Journal of Nutrition, Vol.133 No.11, pp.3805S-3810S	DOI
2004-03	Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-kappa B Chun, Kyung-Soo; Cha, Hyun-Ho; Shin, Jun-Wan; Na, Hye-Kyung; Park, Kwang-Kyun; Chung, Won-Yoon; Surh, Young-Joon Carcinogenesis, Vol.25 No.3, pp.445-454	DOI
2004-09	Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target Kim, Su-Hyeong; Song, Sang-Hyun; Kim, Sang-Gyun; Chun, Kyung-Soo; Lim, So-Young; Na, Hye-Kyung; Kim, Jae Weon; Surh, Young-Joon; Bang, Yung-Jue; Song, Yong-Sang Journal of Cancer Research and Clinical Oncology, Vol.130 No.9, pp.551-560	DOI
2004-09	Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells Kim, Do-Hee; Na, Hye-Kyung; Oh, Tae Young; Kim, Won-Bae; Surh, Young-Joon Biochemical Pharmacology, Vol.68 No.6, pp.1081-1087	DOI
2004-10	Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells Chen, Zhi-Hua; Hurh, Yeon-Jin; Na, Hye-Kyung; Kim, Jung-Hwan; Chun, Young-Jin; Kim, Dong-Hyun; Kang, Kyung-Sun; Cho, Myung-Haing; Surh, Young-Joon Carcinogenesis, Vol.25 No.10, pp.2005-2013	DOI
2004-10	15-Deoxy-Δ12,14-prostaglandin J2 protects against nitrosative PC12 cell death through up-regulation of intracellular gutathione synthesis Lim, So-Young; Jang, Jung-Hee; Na, Hye-Kyung; Lu, Shelly C.; Rahman, Irfan; Surh, Young-Joon Journal of Biological Chemistry, Vol.279 No.44, pp.46263-46270	DOI
2004-12	2-hydroxyestradiol induces oxidative DNA damage and apoptosis in human mammary epithelial cells Hurh, Yeon-Jin; Chen, Zhi-Hua; Na, Hye-Kyung; Han, Soon- Young; Surh, YoungJoon Journal of Toxicology and Environmental Health - Part A, Vol.67 No.23-24, pp.1939-1953	DOI
2005	Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human gastric cancer (AGS) cells Kim, Min-Jung; Kim, Do-Hee; Na, Hye-Kyung; Oh, Tae Young; Shin, Chang-Yell; Surh, Young-Joon Journal of Environmental Pathology, Toxicology and Oncology, Vol.24 No.4, pp.261-269	DOI
2005	Eupatilin inhibits proliferation of ras-transformed human breast epithelial (MCF-10A-ras) cells Kim, Do-Hee; Na, Hye-Kyung; Oh, Tae Young; Shin, Chang-Yell; Surh, Young-Joon Journal of Environmental Pathology, Toxicology and Oncology, Vol.24 No.4, pp.251-259	DOI
2005-01	Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets Kundu, Joydeb Kumar; Mossanda, Kensese S.; Na, Hye-Kyung; Surh, Young-Joon Cancer Letters, Vol.218 No.1, pp.21-31	DOI
2005-10	4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-κB and ERK/MAPK Chen, Zhi-Hua; Na, Hye-Kyung; Hurh, Yeon-Jin; Surh, Young-Joon Toxicology and Applied Pharmacology, Vol.208 No.1, pp.46-56	DOI
2005-11	ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells Na, Hye-Kyung; Inoue, Hiroyasu; Surh, Young-Joon FEBS Letters, Vol.579 No.27, pp.6279-6287	DOI
2005-12	Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicals Surh, Young Joon; Kundu, Joydeb Kumar; Na, Hye-Kyung; Lee, Jeong-Sang Journal of Nutrition, Vol.135 No.12, pp.2993S-3001S	DOI
2006-06	Transcriptional regulation via cysteine thiol modification: A novel molecular strategy for chemoprevention and cytoprotection Na, Hye-Kyung; Surh, Young-Joon Molecular Carcinogenesis, Vol.45 No.6, pp.368-380	DOI
2006-12	Upregulation of VEGF by 15-deoxy-Δ12,14-prostaglandin J2 via heme oxygenase-1 and ERK1/2 signaling in MCF-7 cells Kim, Eun-Hee; Na, Hye-Kyung; Surh, Young-Joon Annals of the New York Academy of Sciences, Vol.1090, pp.375-384	DOI
2007-03	KG-135 inhibits COX-2 expression by blocking the activation of JNK and AP-1 in phorbol ester-stimulated human breast epithelial cells Park, Sin-Aye; Kim, Eun-Hee; Na, Hye-Kyung; Surh, Young-Joon Annals of the New York Academy of Sciences, Vol.1095, pp.545-553	DOI
2007-07	Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-κB and AP-1: IκB kinase and c-Jun-N-terminal kinase as respective potential upstream targets Lee, Jung-Chul; Kundu, Joydeb K.; Hwang, Dal-Mi; Na, Hye-Kyung; Surh, Young-Joon Carcinogenesis, Vol.28 No.7, pp.1491-1498	DOI
2007-09	Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling Li, Mei-Hua; Jang, Jung-Hee; Na, Hye-Kyung; Cha, Young-Nam; Surh, Young-Joon Journal of Biological Chemistry, Vol.282 No.39, pp.28577-28586	DOI
2007-12	Forum original research communication - Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H: quinone oxidoreductase as a potential target Joung, Eun-Joo; Li, Mei-Hua; Lee, Hee Geum; Somparn, Nuntiya; Jung, Young Suk; Na, Hye-Kyung; Kim, Sung-Hoon; Cha, Young-Nam; Surh, Young-Joon Antioxidants and Redox Signaling, Vol.9 No.12, pp.2087-2098	DOI
2007-12	Forum original research communication - Nrf2-mediated heme oxygenase-1 induction confers adaptive survival response to Tetrahydropapaveroline-Induced oxidative PC12 cell death Park, So-Hyun; Jang, Jung-Hee; Li, Mei-Hua; Na, Hye-Kyung; Cha, Young-Nam; Surh, Young-Joon Antioxidants and Redox Signaling, Vol.9 No.12, pp.2075-2086	DOI
2008	Chemopreventive effects of the standardized extract (DA-9601) of Artemisia asiatica on azoxymethane-initiated and dextran sulfate sodium-promoted mouse colon carcinogenesis Kim, Hyun Soo; Kundu, Joydeb Kumar; Lee, Jeong-Sang; Oh, The-Young; Na, Hye-Kyung; Surh, Young-Joon Nutrition and Cancer, Vol.60 No.S1, pp.90-97	DOI
2008-01	Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-κB activation and COX-2 expression in human breast epithelial cells Kim, Jung-Hwan; Na, Hye-Kyung; Pak, Youngmi K.; Lee, Yun-Sil; Lee, Su-Jae; Moon, Aree; Surh, Young-Joon Chemico-Biological Interactions, Vol.171 No.2, pp.133-141	DOI
2008-01	The antitumor ether lipid edelfosine (ET-18-O-CH3) induces apoptosis in H-ras transformed human breast epithelial cells: by blocking ERK1/2 and p38 mitogen-activated protein kinases as potential targets Na, Hye-Kyung; Surh, Young-Joon Asia Pacific Journal of Clinical Nutrition, Vol.17, pp.204-207
2008-02	NF-κB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals Surh, Young-Joon; Na, Hye-Kyung Genes and Nutrition, Vol.2 No.4, pp.313-317	DOI
2008-04	15-Deoxy-Δ 12,14 -prostaglandin J 2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS Kim, Eun-Hee; Na, Hye-Kyung; Kim, Do-Hee; Park, Sin-Aye; Kim, Ha-Na; Song, Na-Young; Surh, Young-Joon Carcinogenesis, Vol.29 No.4, pp.688-695	DOI
2008-04	Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1 Farombi, E. Olatunde; Shrotriya, Sangeeta; Na, Hye-Kyung; Kim, Sung-Hoon; Surh, Young-Joon Food and Chemical Toxicology, Vol.46 No.4, pp.1279-1287	DOI
2008-04	Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG Na, Hye-Kyung; Surh, Young-Joon Food and Chemical Toxicology, Vol.46 No.4, pp.1271-1278	DOI
2008-08	(-)-epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells Na, Hye-Kyung; Kim, Eun-Hee; Jung, Joo-Hee; Lee, Hyun-Hee; Hyun, Jin-Won; Surh, Young-Joon Archives of Biochemistry and Biophysics, Vol.476 No.2, pp.171-177	DOI
2008-10	Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals Surh, Young-Joon; Kundu, Joydeb Kumar; Na, Hye-Kyung Planta Medica, Vol.74 No.13, pp.1526-1539	DOI
2008-12	15-Deoxy-Δ12,14-prostaglandin J2 rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: Potential roles of Akt and ERK1/2 Kim, Ji-Woo; Li, Mei-Hua; Jang, Jung-Hee; Na, Hye-Kyung; Song, Na-Young; Lee, Chan; Johnson, Jeffrey A.; Surh, Young-Joon Biochemical Pharmacology, Vol.76 No.11, pp.1577-1589	DOI
2009	Ginger-derived phenolic substances with cancer preventive and therapeutic potential Kundu, Joydeb Kumar; Na, Hye-Kyung; Surh, Young-Joon Forum of Nutrition, Vol.61, pp.182-192	DOI
2009-03	4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IκB kinase: Potential role of reactive oxygen species Park, Sin-Aye; Na, Hye-Kyung; Kim, Eun-Hee; Cha, Young-Nam; Surh, Young-Joon Cancer Research, Vol.69 No.6, pp.2416-2424	DOI
2009-04	15-Deoxy-Δ12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: Possible roles of iron and ROS Kim, Do-Hee; Kim, Jung-Hyun; Kim, Eun-Hee; Na, Hye-Kyung; Cha, Young-Nam; Chung, Jin Ho; Surh, Young-Joon Carcinogenesis, Vol.30 No.4, pp.645-654	DOI
2009-08	Effects of Exercise on Cyclooxygenase‐2 Expression and Nuclear Factor‐κB DNA Binding in Human Peripheral Blood Mononuclear Cells Kim, Si-Young; Jun, Tae-Won; Lee, Young-Soo; Na, Hye-Kyung; Surh, Young-Joon; Song, Wook Annals of the New York Academy of Sciences, Vol.1171, pp.464-471	DOI
2009-08	15‐Deoxy‐Δ12,14‐prostaglandin J2 Induces Upregulation of Multidrug Resistance‐Associated Protein 1 via Nrf2 Activation in Human Breast Cancer Cells Song, Na-Young; Kim, Do-Hee; Kim, Eun-Hee; Na, Hye-Kyung; Surh, Young-Joon Annals of the New York Academy of Sciences, Vol.1171, pp.210-216	DOI
2009-08	Effects of 15-deoxy-Δ12,14-prostaglandin J2 on the dxpression of p53 in MCF-7 cells Kim, Do-Hee; Kim, Eun-Hee; Na, Hye-Kyung; Surh, Young-Joon Annals of the New York Academy of Sciences, Vol.1171, pp.202-209	DOI
2009-08	Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress Surh, Young-Joon; Kundu, Joydeb Kumar; Li, Mei-Hua; Na, Hye-Kyung; Cha, Young-Nam Archives of Pharmacal Research, Vol.32 No.8, pp.1163-1176	DOI
2009-09	Resveratrol Suppresses Growth of Human Ovarian Cancer Cells in Culture and in a Murine Xenograft Model: Eukaryotic Elongation Factor 1A2 as a Potential Target Lee, Mee-Hyun; Choi, Bu Young; Kundu, Joydeb Kumar; Shin, Young Kee; Na, Hye-Kyung; Surh, Young-Joon Cancer Res; Vol.69(18); pp.7449-7458	DOI
2009-10	Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: Eukaryotic elongation factor 1A2 as a potential target Lee, Mee-Hyun; Choi, Bu Young; Kundu, Joydeb Kumar; Shin, Young Kee; Na, Hye-Kyung; Surh, Young-Joon Cancer Research, Vol.69 No.18, pp.7449-7458	DOI
2009-11	Piceatannol inhibits phorbol ester-induced NF-κB activation and COX-2 expression in cultured human mammary epithelial cells. Liu, Dan; Kim, Do-Hee; Park, Jong-Min; Na, Hye-Kyung; Surh, Young-Joon Nutrition and Cancer, Vol.61 No.6, pp.855-863	DOI
2009-11	Resveratrol and Piceatannol Inhibit iNOS Expression and NF-B Activation in Dextran Sulfate Sodium-Induced Mouse Colitis Youn, Jin; Lee, Jeong-Sang; Na, Hye-Kyung; Kundu, Joydeb Kumar; Surh, Young-Joon Nutrition and Cancer, Vol.61 No.6, pp.847-854	DOI
2010-03	Diallyl Trisulfide Inhibits Phorbol Ester-Induced Tumor Promotion, Activation of AP-1, and Expression of COX-2 in Mouse Skin by Blocking JNK and Akt Signaling Shrotriya, Sangeeta; Kundu, Joydeb Kumar; Na, Hye-Kyung; Surh, Young-Joon Cancer Research, Vol.70 No.5, pp.1932-1940	DOI
2010-07	High-fat diet stimulates IL-1 type I receptor-mediated inflammatory signaling in the skeletal muscle of mice Kim, Seung-Jin; Choi, Youngshim; Jun, Hye-Seung; Kim, Bo-Min; Na, Hye-Kyung; Surh, Young-Jun; Park, Taesun Molecular Nutrition and Food Research, Vol.54 No.7, pp.1014-1020	DOI
2010-08	Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-κB activation and cyclooxygenase-2 expression in human breast epithelial cells: Cysteine 179 of IKKβ as a potential target Son, Pil-Soon; Park, Sin-Aye; Na, Hye-Kyung; Jue, Dae-Myung; Kim, Sanghee; Surh, Young-Joon Carcinogenesis, Vol.31 No.8, pp.1442-1449	DOI
2010-09	Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling Lee, Hyun-Hee; Park, Sin-Aye; Almazari, Inas; Kim, Eun-Hee; Na, Hye-Kyung; Surh, Young-Joon Archives of Biochemistry and Biophysics, Vol.501 No.1, pp.142-150	DOI
2010-11	A formulated red ginseng extract rescues PC12 cells from PCB-induced oxidative cell death through Nrf2-mediated upregulation of heme oxygenase-1 and glutamate cysteine ligase Park, So-Hyun; Jang, Jung-Hee; Chen, Chu-Yue; Na, Hye-Kyung; Surh, Young-Joon Toxicology, Vol.278 No.1, pp.131-139	DOI
2010-12	TNF-α induces expression of urokinase-type plasminogen activator and β-catenin activation through generation of ROS in human breast epithelial cells Kim, Min-Jung; Kim, Do-Hee; Na, Hye-Kyung; Surh, Young-Joon Biochemical Pharmacology, Vol.80 No.12, pp.2092-2100	DOI
2010-12	Nrf2-mediated heme oxygenase-1 upregulation as adaptive survival response to glucose deprivation-induced apoptosis in HepG2 cells Lee, Hee Geum; Li, Mei-Hua; Joung, Eun-Joo; Na, Hye-Kyung; Cha, Young-Nam; Surh, Young-Joon Antioxidants and Redox Signaling, Vol.13 No.11, pp.1639-1648	DOI
2011-06	Zerumbone Induces Heme Oxygenase-1 Expression in Mouse Skin and Cultured Murine Epidermal Cells through Activation of Nrf2 Shin, Jun-Wan; Ohnishi, Kohta; Murakami, Akira; Lee, Jeong-Sang; Kundu, Joydeb Kumar; Na, Hye-Kyung; Ohigashi, Hajime; Surh, Young-Joon Cancer Prevention Research, Vol.4 No.6, pp.860-870	DOI
2011-07	Introduction to Nutrition and Physical Activity in Aging, Obesity, and Cancer Surh, Young-Joon; Dashwood, Roderick H.; Na, Hye-Kyung; Ji, Li Li Annals of the New York Academy of Sciences, Vol.1229 No.1, pp.VII-VIII	DOI
2011-08	Multidrug Resistance-Associated Protein 1 Mediates 15-Deoxy-Δ12,14-prostaglandin J2-Induced Expression of Glutamate Cysteine Ligase Expression via Nrf2 Signaling in Human Breast Cancer Cells Song, Na-Young; Kim, Do-Hee; Kim, Eun-Hee; Na, Hye-Kyung; Kim, Nam-Jung; Suh, Young-Ger; Surh, Young-Joon Chemical Research in Toxicology, Vol.24 No.8, pp.1231-1241	DOI
2011-08	Molecular mechanism underlying anti-apoptotic and anti-inflammatory effects of Mamao (Antidesma thwaitesianum Mull. Arg.) polyphenolics in human breast epithelial cells Puangpronpitag, Darunee; Yongvanit, Puangrat; Boonsiri, Patcharee; Suttajit, Maitree; Areejitranusorn, Premjai; Na, Hye-Kyung; Surh, Young-Joon Food Chemistry, Vol.127 No.4, pp.1450-1458	DOI
2011-11	15-Deoxy-Δ12,14-prostaglandin J2, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling Surh, Young-Joon; Na, Hye-Kyung; Park, Jong-Min; Lee, Ha-Na; Kim, Wonki; Yoon, In-Soo; Kim, Dae-Duk Biochemical Pharmacology, Vol.82 No.10, pp.1335-1351	DOI
2011-11	Docosahexaenoic Acid Inhibits UVB-Induced Activation of NF-kappa B and Expression of COX-2 and NOX-4 in HR-1 Hairless Mouse Skin by Blocking MSK1 Signaling Rahman, Md Mostafizur; Kundu, Joydeb Kumar; Shin, Jun-Wan; Na, Hye-Kyung; Surh, Young-Joon PLoS ONE, Vol.6 No.11, p. e28065	DOI
2011-11	15-Hydroxyprostaglandin dehydrogenase as a novel molecular target for cancer chemoprevention and therapy Na, Hye-Kyung; Park, Jong-Min; Lee, Hee Geum; Lee, Ha-Na; Myung, Seung-Jae; Surh, Young-Joon Biochemical Pharmacology, Vol.82 No.10, pp.1352-1360	DOI
2012-02	Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target Almazari, Inas; Park, Jong-Min; Park, Sin-Aye; Suh, Jin-Young; Na, Hye-Kyung; Cha, Young-Nam; Surh, Young-Joon Carcinogenesis, Vol.33 No.2, pp.368-376	DOI
2012-08	Resveratrol suppresses 4-hydroxyestradiol-induced transformation of human breast epithelial cells by blocking I kappa B kinase beta-NF-kappa B signalling Park, Sin-Aye; Na, Hye-Kyung; Surh, Young-Joon Free Radical Research, Vol.46 No.8, pp.1051-1057	DOI
2012-11	Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1 Na, Hye-Kyung; Kim, Eun-Hee; Choi, Min-Ah; Park, Jong-Min; Kim, Do-Hee; Surh, Young-Joon Biochemical Pharmacology, Vol.84 No.10, pp.1241-1250	DOI

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