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Showing results 1 to 33 of 33

Issue Date	Title / Author(s) / Citation	File
2008-12	Blockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy Kim, Jeong Hun; Kim, Jin Hyoung; Yu, Young Suk; Cho, Chang Sik; Kim, Kyu-Won J Cereb Blood Flow Metab. 29(3):621-628	link
2009	Neurotrophin Receptors TrkA and TrkB in Retinoblastoma Are Differentially Expressed Depending on Cellular Differentiation Kim, Jeong Hun; Kim, Jin Hyoung; Kim, Dong Hun; Cho, Chang Sik; Yu, Young Suk; Kim, Kyu-Won; Jun, Hyoung-Oh TUMOR BIOLOGY; Vol.30 ; 233-241	DOI
2009-03	Blockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy Kim, Jeong Hun; Kim, Jin Hyoung; Yu, Young Suk; Cho, Chang Sik; Kim, Kyu-Won JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM; Vol.29 3; 621-628	DOI
2010-03	Differential Roles of Matrix Metalloproteinase-9 and-2, Depending on Proliferation or Differentiation of Retinoblastoma Cells Kim, Jeong Hun; Kim, Jin Hyoung; Cho, Chang Sik; Jun, Hyoung Oh; Yu, Young Suk; Kim, Kyu-Won; Kim, Dong Hun INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE; Vol.51 3; 1783-1788	DOI
2013-06	Animal models of diabetic retinopathy: doors to investigate pathogenesis and potential therapeutics Jo, Dong Hyun; Cho, Chang Sik; Kim, Jin Hyoung; Jun, Hyoung Oh; Kim, Jeong Hun Journal of Biomedical Science, Vol.20 No.1, p. 38	DOI
2014-10	Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1 alpha destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors Jo, Dong Hyun; An, Hongchan; Chang, Dong-Jo; Baek, Yi-Yong; Cho, Chang Sik; Jun, Hyoung Oh; Park, So-Jung; Kim, Jin Hyoung; Lee, Ho-Young; Kim, Kyu-Won; Lee, Jeewoo; Park, Hyun-Ju; Kim, Young-Myeong; Suh, Young-Ger; Kim, Jeong Hun Journal of Molecular Medicine, Vol.92 No.10, pp.1083-1092	DOI
2014-11	STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Jo, Dong Hyun; Kim, Jin Hyoung; Cho, Chang Sik; Cho, Young-Lai; Jun, Hyoung Oh; Yu, Young Suk; Min, Jeong-Ki; Kim, Jeong Hun Oncotarget, Vol.5 No.22, pp.11513-11525	DOI
2015-07	Intravitreally injected anti-VEGF antibody reduces brown fat in neonatal mice Jo, Dong Hyun; Park, Sung Wook; Cho, Chang Sik; Powner, Michael B.; Kim, Jin Hyoung; Fruttiger, Marcus; Kim, Jeong Hun PLoS ONE, Vol.10 No.7, p. e0134308	DOI
2017-11	Chronological Changes in Tip Cells during Sprouting Angiogenesis of Development of the Retinal Vasculature in Newborn Mice Cho, Chang Sik; Lee, Sang-Mok; Lee, Byung Joo; Jo, Dong Hyun; Kim, Jin Hyoung; Kim, Jeong Hun; Yu, Young Suk Current Eye Research, Vol.42 No.11, pp.1511-1517	DOI
2018-07	Lactic acid upregulates VEGF expression in macrophages and facilitates choroidal neovascularization Song, Juha; Lee, Kihwang; Park, Sung Wook; Chung, Hyewon; Jung, Daun; Na, Yi Rang; Quan, Hailian; Cho, Chang Sik; Che, Jeong-Hwan; Kim, Jeong Hun; Park, Jae-Hak; Seok, Seung Hyeok Investigative Ophthalmology and Visual Science, Vol.59 No.8, pp.3747-3754	DOI
2018-10	Novel hypoxia-inducible factor 1 alpha (HIF-1α) inhibitors for angiogenesis-related ocular diseases: Discovery of a novel scaffold via ring-truncation strategy An, Hongchan; Lee, Seungbeom; Lee, Jung Mm; Jo, Dong Hyun; Kim, Joohwan; Jeong, Yoo-Seong; Heo, Mi Jeong; Cho, Chang Sik; Choi, Hoon; Seo, Ji Hae; Hwang, Seyeon; Lim, Jihye; Kim, Taewoo; Jun, Hyoung Oh; Sim, Jaehoon; Lim, Changjin; Hur, Joonseong; Ahn, Jungmin; Kim, Hyun Su; Seo, Seung-Yong; Na, Younghwa; Kim, Seok-Ho; Lee, Jeewoo; Lee, Jeeyeon; Chung, Suk-Jae; Kyu, Young-Myeong; Kim, Kyu-Won; Kim, Sang Geon; Kim, Jeong Hun; Suh, Young-Ger Journal of Medicinal Chemistry, Vol.61 No.20, pp.9266-9286	DOI
2018-12	Depthwise-controlled scleral insertion of microneedles for drug delivery to the back of the eye Park, Seung Hyun; Jo, Dong Hyun; Cho, Chang Sik; Lee, KangJu; Kim, Jin Hyoung; Ryu, Suho; Joo, Chulmin; Kim, Jeong Hun; Ryu, WonHyoung European Journal of Pharmaceutics and Biopharmaceutics, Vol.133, pp.31-41	DOI
2019-01	Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus Jo, Dong Hyun; Koo, Taeyoung; Cho, Chang Sik; Kim, Jin Hyoung; Kim, Jin-Soo; Kim, Jeong Hun Molecular Therapy, Vol.27 No.1, pp.130-136	DOI
2019-02	Interaction between microglia and retinal pigment epithelial cells determines the integrity of outer blood-retinal barrier in diabetic retinopathy Jo, Dong Hyun; Yun, Jang-Hyuk; Cho, Chang Sik; Kim, Jin Hyoung; Kim, Jeong Hun; Cho, Chung-Hyun GLIA, Vol.67 No.2, pp.321-331	DOI
2019-04	Development of a patient-derived xenograft model of glioblastoma via intravitreal injection in mice Lee, Jooyoung; Jo, Dong Hyun; Kim, Jin Hyoung; Cho, Chang Sik; Han, Jiwon Esther; Kim, Yona; Park, Hyoungwoo; Yoo, Seung Ho; Yu, Young Suk; Moon, Hyo Eun; Park, Hye Ran; Kim, Dong Gyu; Kim, Jeong Hun; Paek, Sun Ha Experimental and Molecular Medicine, Vol.51 No.4, pp.1-9	DOI
2019-10	CRISPR-Cas9-mediated therapeutic editing of Rpe65 ameliorates the disease phenotypes in a mouse model of Leber congenital amaurosis Jo, Dong Hyun; Song, Dong Woo; Cho, Chang Sik; Kim, Un Gi; Lee, Kyu Jun; Lee, Kihwang; Park, Sung Wook; Kim, Daesik; Kim, Jin Hyoung; Kim, Jin-Soo; Kim, Seokjoong; Kim, Jeong Hun; Lee, Jung Min Science advances, Vol.5 No.10	DOI
2020-11	Intracellular amyloid-β disrupts tight junctions of the retinal pigment epithelium via NF-κB activation Jo, Dong Hyun; Cho, Chang Sik; Kim, Jin Hyoung; Kim, Jeong Hun Neurobiology of Aging, Vol.95, pp.115-122	DOI
2020-12	Histamine causes an imbalance between pro-angiogenic and anti-angiogenic factors in the retinal pigment epithelium of diabetic retina via H4 receptor/p38 MAPK axis Lee, Byung Joo; Byeon, Hye Eun; Cho, Chang Sik; Kim, Young Ho; Kim, Jin Hyoung; Che, Jeong-Hwan; Seok, Seung Hyeok; Kwon, Jung-Won; Kim, Jeong Hun; Lee, Kihwang BMJ Open Diabetes Research and Care, Vol.8 No.2, p. e001710	DOI
2021-07	Antitumor Activity of Novel Signal Transducer and Activator of Transcription 3 Inhibitors on Retinoblastoma Jo, Dong Hyun; Lee, Seungbeom; Bak, Eunoo; Cho, Chang Sik; Han, Young Taek; Kim, Kyeojin; Suh, Young-Ger; Kim, Jeong Hun Molecular Pharmacology, Vol.100 No.1, pp.63-72	DOI
2021-08	High-purity production and precise editing of DNA base editing ribonucleoproteins Jang, Hyeon-Ki; Jo, Dong Hyun; Lee, Seu-Na; Cho, Chang Sik; Jeong, You Kyeong; Jung, Youngri; Yu, Jihyeon; Kim, Jeong Hun; Woo, Jae-Sung; Bae, Sangsu Science Advances, Vol.7 No.35	DOI
2021-10	Corneal lymphangiogenesis in dry eye disease is regulated by substance P/ neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 3 Lee, Seok Jae; Im, Sang-Taek; Wu, Jun; Cho, Chang Sik; Jo, Dong Hyun; Chen, Yihe; Dana, Reza; Kim, Jeong Hun; Lee, Sang-Mok Ocular Surface, Vol.22, pp.72-79	DOI
2021-10	Giant Y79 retinoblastoma cells contain functionally active T-type calcium channels Kim, Sooyun; Guzman, Segundo Jose; Jo, Dong Hyun; Cho, Chang Sik; Kim, Jeong Hun Pflugers Archiv European Journal of Physiology, Vol.473 No.10, pp.1631-1639	DOI
2021-12	Specific ablation of PDGFRβ-overexpressing pericytes with antibody-drug conjugate potently inhibits pathologic ocular neovascularization in mouse models Lee, Seok Jae; Kim, Soohyun; Jo, Dong Hyun; Cho, Chang Sik; Kim, Su Ree; Kang, Dongmin; Chae, Jisu; Yoo, Duck Kyun; Ha, Suji; Chung, Junho; Kim, Jeong Hun Communications Medicine, Vol.1 No.1, p. 58	DOI
2022-02	Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases Jang, Hyewon; Jo, Dong Hyun; Cho, Chang Sik; Shin, Jeong Hong; Seo, Jung Hwa; Yu, Goosang; Gopalappa, Ramu; Kim, Daesik; Cho, Sung-Rae; Kim, Jeong Hun; Kim, Hyongbum Henry Nature Biomedical Engineering, Vol.6 No.2, pp.181-194	DOI
2022-06	Self-Plugging Microneedle (SPM) for Intravitreal Drug Delivery Lee, KangJu; Park, SeungHyun; Jo, Dong Hyun; Cho, Chang Sik; Jang, Ha Young; Yi, Jiyeon; Kang, Minkyung; Kim, Jaeho; Jung, Ho Yun; Kim, Jeong Hun; Ryu, WonHyoung; Khademhosseini, Ali Advanced healthcare materials, Vol.11 No.12, p. 2102599	DOI
2022-10	Establishment and Characterization of Carboplatin-Resistant Retinoblastoma Cell Lines Cho, Chang Sik; Jo, Dong Hyun; Kim, Jin Hyoung; Kim, Jeong Hun Molecules and Cells, Vol.45 No.10, pp.729-737	DOI
2023-01	Application of Base Editor-Mediated Genome Editing in Mouse Retina Wu, Jun; Cho, Chang Sik; Jo, Dong Hyun; Kim, Jeong Hun Methods in molecular biology (Clifton, N.J.), Vol.2606, pp.179-188	DOI
2023-02	Enhancement of Gene Editing and Base Editing with Therapeutic Ribonucleoproteins through In Vivo Delivery Based on Absorptive Silica Nanoconstruct Kim, Seongchan; Jeong, You Kyeong; Cho, Chang Sik; Lee, SeokHoon; Sohn, Chang Ho; Kim, Jeong Hun; Jeong, Youngdo; Jo, Dong Hyun; Bae, Sangsu; Lee, Hyojin Advanced Healthcare Materials, Vol.12 No.4, p. 2201825	DOI
2023-03	Visual function restoration in a mouse model of Leber congenital amaurosis via therapeutic base editing Jo, Dong Hyun; Jang, Hyeon-Ki; Cho, Chang Sik; Han, Jun Hee; Ryu, Gahee; Jung, Youngri; Bae, Sangsu; Kim, Jeong Hun Molecular Therapy - Nucleic Acids, Vol.31, pp.16-27	DOI
2023-07	Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice Kim, Sojin; Song, Yong Keun; Cho, Chang Sik; Kim, Hyo Jung; Fang, Sungsoon; Jo, Dong Hyun; Kim, Hyunkyung Oncology Reports, Vol.50 No.1, p. 146	DOI
2023-11	Activation of Lysosomal Function Ameliorates Amyloid-β-Induced Tight Junction Disruption in the Retinal Pigment Epithelium Jo, Dong Hyun; Lee, Su Hyun; Jeon, Minsol; Cho, Chang Sik; Kim, Da-Eun; Kim, Hyunkyung; Kim, Jeong Hun Molecules and Cells, Vol.46 No.11, pp.675-687	DOI
2024-02	Mitochondrial transplantation attenuates oligomeric amyloid-beta-induced mitochondrial dysfunction and tight junction protein destruction in retinal pigment epithelium Noh, Sung-Eun; Lee, Seok Jae; Cho, Chang Sik; Jo, Dong Hyun; Park, Kyu Sang; Kim, Jeong Hun Free Radical Biology and Medicine, Vol.212, pp.10-21	DOI
2024-05	IL-10-induced modulation of macrophage polarization suppresses outer-blood-retinal barrier disruption in the streptozotocin-induced early diabetic retinopathy mouse model Lee, Seok Jae; Noh, Sung-Eun; Jo, Dong Hyun; Cho, Chang Sik; Park, Kyu-Sang; Kim, Jeong Hun FASEB Journal, Vol.38 No.9, p. e23638	DOI