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Spontaneous corneal melting during pregnancy: a case report

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Authors
Oh, Joo Youn; Kim, Mee Kum; Park, Joong Shin; Wee, Won Ryang
Issue Date
2009-05-26
Publisher
BioMed Central
Citation
Cases Journal, 2(1):7444
Description
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Abstract

Introduction
Biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting.


Case presentation
A 33-year-old Asian female who underwent penetrating keratoplasty in both eyes developed corneal melting in the right eye and marginal keratitis in the left eye in her fifth month of pregnancy. Marginal keratitis in the left eye immediately subsided with topical steroid therapy. However, spontaneous corneal melting progressed in the right eye, despite oral steroid therapy and amniotic membrane transplantation. We performed tectonic penetrating keratoplasty and corneoscleral grafting in the right eye.


Conclusion
We advise caution in the ophthalmologic care of pregnant patients who have preexisting corneal thinning disorders or who have undergone multiple corneal surgeries, because physiologic changes during pregnancy might contribute to corneal changes leading to spontaneous melting especially in patients with compromised cornea.
Language
English
URI
https://hdl.handle.net/10371/100323
DOI
https://doi.org/10.1186/1757-1626-2-7444
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College of Medicine/School of Medicine (의과대학/대학원)Ophthalmology (안과학전공)Journal Papers (저널논문_안과학전공)
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