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Local recurrence of hepatocellular carcinoma after segmental transarterial chemoembolization: risk estimates based on multiple prognostic factors
DC Field | Value | Language |
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dc.contributor.author | Park, Seung Hyun | - |
dc.contributor.author | Cho, Yun Ku | - |
dc.contributor.author | Ahn, Yong-Sik | - |
dc.contributor.author | Park, Yoon-Ok | - |
dc.contributor.author | Kim, Jae Kyun | - |
dc.contributor.author | Chung, Jin Wook | - |
dc.date.accessioned | 2009-10-08T06:18:24Z | - |
dc.date.available | 2009-10-08T06:18:24Z | - |
dc.date.issued | 2007-04-11 | - |
dc.identifier.citation | Korean J Radiol 2007;8(2):111-119 | en |
dc.identifier.issn | 1229-6929 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17420628 | - |
dc.identifier.uri | https://hdl.handle.net/10371/10341 | - |
dc.description.abstract | OBJECTIVE: To determine the prognostic factors for local recurrence of nodular hepatocellular carcinoma after segmental transarterial chemoembolization. MATERIALS AND METHODS: Seventy-four nodular hepatocellular carcinoma tumors < or = 5 cm were retrospectively analyzed for local recurrence after segmental transarterial chemoembolization using follow-up CT images (median follow-up of 17 months, 4-77 months in range). The tumors were divided into four groups (IA, IB, IIA, and IIB) according to whether the one-month follow-up CT imaging, after segmental transarterial chemoembolization, showed homogeneous (Group I) or inhomogeneous (Group II) iodized oil accumulation, or whether the tumors were located within the liver segment (Group A) or in a segmental border zone (Group B). Comparison of tumor characteristics between Group IA and the other three groups was performed using the chi-square test. Local recurrence rates were compared among the groups using the Kaplan-Meier estimation and log rank test. RESULTS: Local tumor recurrence occurred in 19 hepatocellular carcinoma tumors (25.7%). There were: 28, 18, 17, and 11 tumors in Group IA, IB, IIA, and IIB, respectively. One of 28 (3.6%) tumors in Group IA, and 18 of 46 (39.1%) tumors in the other three groups showed local recurrence. Comparisons between Group IA and the other three groups showed that the tumor characteristics were similar. One-, two-, and three-year estimated local recurrence rates in Group IA were 0%, 11.1%, and 11.1%, respectively. The difference between Group IA and the other three groups was statistically significant (p = 0.000). CONCLUSION: An acceptably low rate of local recurrence was observed for small or intermediate nodular tumors located within the liver segment with homogeneous iodized oil accumulation. | en |
dc.language.iso | en | - |
dc.publisher | The Korean Radiological Society | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Carcinoma, Hepatocellular/*pathology/radiography/*therapy | en |
dc.subject | Chemoembolization, Therapeutic/*methods | en |
dc.subject | Chi-Square Distribution | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Iodized Oil/administration & dosage | en |
dc.subject | Liver Neoplasms/*pathology/radiography/*therapy | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Neoplasm Recurrence, Local/radiography | en |
dc.subject | Prognosis | en |
dc.subject | Retrospective Studies | en |
dc.subject | Risk Factors | en |
dc.subject | Tomography, X-Ray Computed | en |
dc.title | Local recurrence of hepatocellular carcinoma after segmental transarterial chemoembolization: risk estimates based on multiple prognostic factors | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 박성현 | - |
dc.contributor.AlternativeAuthor | 조윤구 | - |
dc.contributor.AlternativeAuthor | 안용식 | - |
dc.contributor.AlternativeAuthor | 박윤옥 | - |
dc.contributor.AlternativeAuthor | 김재균 | - |
dc.contributor.AlternativeAuthor | 정진욱 | - |
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