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Local recurrence of hepatocellular carcinoma after segmental transarterial chemoembolization: risk estimates based on multiple prognostic factors

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dc.contributor.authorPark, Seung Hyun-
dc.contributor.authorCho, Yun Ku-
dc.contributor.authorAhn, Yong-Sik-
dc.contributor.authorPark, Yoon-Ok-
dc.contributor.authorKim, Jae Kyun-
dc.contributor.authorChung, Jin Wook-
dc.date.accessioned2009-10-08T06:18:24Z-
dc.date.available2009-10-08T06:18:24Z-
dc.date.issued2007-04-11-
dc.identifier.citationKorean J Radiol 2007;8(2):111-119en
dc.identifier.issn1229-6929 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17420628-
dc.identifier.urihttps://hdl.handle.net/10371/10341-
dc.description.abstractOBJECTIVE: To determine the prognostic factors for local recurrence of nodular hepatocellular carcinoma after segmental transarterial chemoembolization. MATERIALS AND METHODS: Seventy-four nodular hepatocellular carcinoma tumors < or = 5 cm were retrospectively analyzed for local recurrence after segmental transarterial chemoembolization using follow-up CT images (median follow-up of 17 months, 4-77 months in range). The tumors were divided into four groups (IA, IB, IIA, and IIB) according to whether the one-month follow-up CT imaging, after segmental transarterial chemoembolization, showed homogeneous (Group I) or inhomogeneous (Group II) iodized oil accumulation, or whether the tumors were located within the liver segment (Group A) or in a segmental border zone (Group B). Comparison of tumor characteristics between Group IA and the other three groups was performed using the chi-square test. Local recurrence rates were compared among the groups using the Kaplan-Meier estimation and log rank test. RESULTS: Local tumor recurrence occurred in 19 hepatocellular carcinoma tumors (25.7%). There were: 28, 18, 17, and 11 tumors in Group IA, IB, IIA, and IIB, respectively. One of 28 (3.6%) tumors in Group IA, and 18 of 46 (39.1%) tumors in the other three groups showed local recurrence. Comparisons between Group IA and the other three groups showed that the tumor characteristics were similar. One-, two-, and three-year estimated local recurrence rates in Group IA were 0%, 11.1%, and 11.1%, respectively. The difference between Group IA and the other three groups was statistically significant (p = 0.000). CONCLUSION: An acceptably low rate of local recurrence was observed for small or intermediate nodular tumors located within the liver segment with homogeneous iodized oil accumulation.en
dc.language.isoen-
dc.publisherThe Korean Radiological Societyen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCarcinoma, Hepatocellular/*pathology/radiography/*therapyen
dc.subjectChemoembolization, Therapeutic/*methodsen
dc.subjectChi-Square Distributionen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectIodized Oil/administration & dosageen
dc.subjectLiver Neoplasms/*pathology/radiography/*therapyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeoplasm Recurrence, Local/radiographyen
dc.subjectPrognosisen
dc.subjectRetrospective Studiesen
dc.subjectRisk Factorsen
dc.subjectTomography, X-Ray Computeden
dc.titleLocal recurrence of hepatocellular carcinoma after segmental transarterial chemoembolization: risk estimates based on multiple prognostic factorsen
dc.typeArticleen
dc.contributor.AlternativeAuthor박성현-
dc.contributor.AlternativeAuthor조윤구-
dc.contributor.AlternativeAuthor안용식-
dc.contributor.AlternativeAuthor박윤옥-
dc.contributor.AlternativeAuthor김재균-
dc.contributor.AlternativeAuthor정진욱-
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Radiation Applied Life Science (대학원 협동과정 방사선응용생명과학전공)Journal Papers (저널논문_방사선응용생명과학전공)
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