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Contrast-enhanced MRI combined with MR cholangiopancreatography for the evaluation of patients with biliary strictures: differentiation of malignant from benign bile duct strictures

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dc.contributor.authorKim, Ji Yang-
dc.contributor.authorLee, Jeong Min-
dc.contributor.authorHan, Joon Koo-
dc.contributor.authorKim, Se Hyung-
dc.contributor.authorLee, Jae Young-
dc.contributor.authorChoi, Jin Young-
dc.contributor.authorKim, Soo Jin-
dc.contributor.authorKim, Hyuck Jung-
dc.contributor.authorKim, Ki Hyeun-
dc.contributor.authorChoi, Byung Ihn-
dc.date.accessioned2009-10-14T10:22:25Z-
dc.date.available2009-10-14T10:22:25Z-
dc.date.issued2007-07-12-
dc.identifier.citationJ Magn Reson Imaging 2007;26:304-312en
dc.identifier.issn1053-1807 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17623893-
dc.identifier.urihttps://hdl.handle.net/10371/10446-
dc.description.abstractPURPOSE: To determine imaging criteria for the combined use of contrast-enhanced (CE)-MRI and MR cholangiopancreatography (MRCP) to differentiate malignant from benign biliary strictures. MATERIALS AND METHODS: A total of 44 patients with biliary stricture who had undergone unenhanced, MRCP, and dynamic MRI were identified from radiological and surgical databases. Two radiologists analyzed MR features for asymmetry, luminal irregularity, abrupt narrowing, outer margin, signal intensity (SI) on T2-weighted (T2W) images, and hyperenhancement relative to liver parenchyma during portal phase. The wall thickness and length of the narrowed segment were measured. MR findings relevant as predictors were identified using a Chi-square or Fisher's exact test and the odds ratio (OR). RESULTS: The presence of hyperenhancement relative to liver parenchyma, length > 12 mm, wall thickness > 3 mm, indistinct outer margin, luminal irregularity, and asymmetry of strictured bile duct were significant factors for malignancy (P < 0.05). Malignant strictures were significantly thicker (5.0 +/- 2.0 mm) and longer (27.0 +/- 13.6 mm) than benign strictures. When any three or more of these six criteria were used in combination, we could identify 100% of malignant strictures and 87.0% of benign strictures. CONCLUSION: The combined use of CE-MRI and MRCP helped to define the criteria for differentiating malignant from benign biliary strictures in our data.en
dc.language.isoenen
dc.publisherJohn Wiley & Sonsen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBile Duct Diseases/*diagnosis/pathologyen
dc.subjectBile Ducts/*pathologyen
dc.subjectBiliary Tract Diseases/*diagnosis/pathologyen
dc.subjectCholangiopancreatography, Magnetic Resonance/*methodsen
dc.subjectCholestasis/pathologyen
dc.subjectContrast Media/pharmacologyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLiver/metabolismen
dc.subjectMagnetic Resonance Imaging/*methodsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.titleContrast-enhanced MRI combined with MR cholangiopancreatography for the evaluation of patients with biliary strictures: differentiation of malignant from benign bile duct stricturesen
dc.typeArticleen
dc.contributor.AlternativeAuthor김지양-
dc.contributor.AlternativeAuthor이정민-
dc.contributor.AlternativeAuthor한준구-
dc.contributor.AlternativeAuthor김세형-
dc.contributor.AlternativeAuthor이재영-
dc.contributor.AlternativeAuthor최진영-
dc.contributor.AlternativeAuthor김수진-
dc.contributor.AlternativeAuthor김혁중-
dc.contributor.AlternativeAuthor김기현-
dc.contributor.AlternativeAuthor최병인-
dc.identifier.doi10.1002/jmri.20973-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Radiation Applied Life Science (대학원 협동과정 방사선응용생명과학전공)Journal Papers (저널논문_방사선응용생명과학전공)
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