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Design and biological activity of synthetic oligopeptides with Pro-His-Ser-Arg-Asn (PHSRN) and Arg-Gly-Asp (RGD) motifs for human osteoblast-like cell (MG-63) adhesion
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Tae-Il | - |
| dc.contributor.author | Jang, Jun-Hyeog | - |
| dc.contributor.author | Lee, Yong-Moo | - |
| dc.contributor.author | Ryu, In-Cheol | - |
| dc.contributor.author | Chung, Chong-Pyoung | - |
| dc.contributor.author | Han, Soo-Boo | - |
| dc.contributor.author | Choi, Sang-Mook | - |
| dc.contributor.author | Ku, Young | - |
| dc.date.accessioned | 2009-10-29T22:12:38Z | - |
| dc.date.available | 2009-10-29T22:12:38Z | - |
| dc.date.issued | 2002 | - |
| dc.identifier.citation | Biotechnol Letters 24, 2029-2033 | en |
| dc.identifier.issn | 0141-5492 | - |
| dc.identifier.uri | https://hdl.handle.net/10371/10924 | - |
| dc.description.abstract | A synthetic oligopeptide, composed of Arg-Gly-Asp (RGD) and its synergistic Pro-His-Ser-Arg-Asn (PHSRN) motifs and a six glycines (G6) linker, promoted human osteoblast-like cell (MG-63) adhesion, spreading and mitogen-activated protein kinase (MAPK) activity in a similar manner to a positive fibronectin control. This synthetic oligopeptide may therefore be a useful osteo-inductive material. | en |
| dc.description.sponsorship | This work was supported by the Korean Science and
Engineering Foundation (KOSEF) through the Intellectual Biointerface Engineering Center (IBEC) at Seoul National University. | en |
| dc.language.iso | en | - |
| dc.publisher | Springer Verlag | en |
| dc.subject | fibronectin | en |
| dc.subject | mitogen-activated protein kinase | en |
| dc.subject | oligopeptides | en |
| dc.subject | osteoblast-like cell | en |
| dc.title | Design and biological activity of synthetic oligopeptides with Pro-His-Ser-Arg-Asn (PHSRN) and Arg-Gly-Asp (RGD) motifs for human osteoblast-like cell (MG-63) adhesion | en |
| dc.type | Article | en |
| dc.contributor.AlternativeAuthor | 김태일 | - |
| dc.contributor.AlternativeAuthor | 장준형 | - |
| dc.contributor.AlternativeAuthor | 이용무 | - |
| dc.contributor.AlternativeAuthor | 류인철 | - |
| dc.contributor.AlternativeAuthor | 정종평 | - |
| dc.contributor.AlternativeAuthor | 한수부 | - |
| dc.contributor.AlternativeAuthor | 최상묵 | - |
| dc.contributor.AlternativeAuthor | 구영 | - |
| dc.identifier.doi | 10.1023/A:1021368519336 | - |
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