Browse

Differential correlation of frontal and parietal activity with the number of alternatives for cued choice saccades

DC Field Value Language
dc.contributor.authorLee, Kyoung-Min-
dc.contributor.authorWade, Alex R-
dc.contributor.authorLee, Byeong-Taek-
dc.date.accessioned2009-11-04T03:26:39Z-
dc.date.available2009-11-04T03:26:39Z-
dc.date.issued2006-
dc.identifier.citationNeuroimage. 33, 307-315en
dc.identifier.issn1053-8119 (Print)-
dc.identifier.urihttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4KNKBW8-2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=764430f87392f8f20a13b6c90a276efb-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16919481-
dc.identifier.urihttps://hdl.handle.net/10371/11083-
dc.description.abstractThe time taken to choose a response appropriate for a cue increases with the number of potential response options (Hick's law). We used this temporal constraint of choice behavior in event-related fMRI experiments to identify brain areas carrying out the translation from a cue stimulus to response: Since the process takes longer with more alternatives, the activity of the areas would increase in correlation with the number of alternatives (NA) available at the time of choice decision. During a choice saccade task in which one target is selected among many alternatives based on the color of a cue in the center, the frontal eye fields (FEF) and intraparietal sulcus (IPS) were activated. Within these regions, signals were correlated with NA at the medial part of the FEF and the posterior part of the IPS, but not at the lateral FEF and anterior IPS. This suggests a functional differentiation within each cortical region. Furthermore, given the separate fronto-parietal projections linking sub-regions that are alike in NA-correlation, cognitive steps for choice decision may occur in different networks of the sub-regions: i.e., the stimulus-response translation step in a network of the posterior IPS and medial FEF, and response execution in the anterior IPS/lateral FEF network.en
dc.description.sponsorshipThis work was supported by a grant (M103KV010021-
03K2201-02120) from Brain Research Center of the 21st Century
Frontier Research Program funded by the Ministry of Science and
Technology of Republic of Korea and by P30_EY006883 and the
Smith-Kettlewell Eye Research Institute.
en
dc.language.isoen-
dc.publisherElsevieren
dc.subject*Cuesen
dc.subjectData Interpretation, Statisticalen
dc.subjectFrontal Lobe/*physiologyen
dc.subjectImage Processing, Computer-Assisteden
dc.subjectMagnetic Resonance Imagingen
dc.subjectParietal Lobe/*physiologyen
dc.subjectPhotic Stimulationen
dc.subjectReaction Time/physiologyen
dc.subjectSaccades/*physiologyen
dc.subjectVisual Fields/physiologyen
dc.titleDifferential correlation of frontal and parietal activity with the number of alternatives for cued choice saccadesen
dc.typeArticleen
dc.contributor.AlternativeAuthor이경민-
dc.contributor.AlternativeAuthor이병택-
dc.identifier.doi10.1016/j.neuroimage.2006.06.039-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
Files in This Item:
There are no files associated with this item.
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse