S-Space College of Medicine/School of Medicine (의과대학/대학원) Otorhinolaryngology (이비인후과학전공) Journal Papers (저널논문_이비인후과학전공)
Bronchial hyperresponsiveness in young children with allergic rhinitis and its risk factors
- Choi, S. H.; Yoo, Y.; Yu, J.; Rhee, C.-S.; Min, Y.-G.; Koh, Y. Y.
- Issue Date
- Allergy 2007;62:1051-1056
- Allergens/adverse effects/immunology; Bronchial Hyperreactivity/blood/*epidemiology/immunology/physiopathology; Bronchial Provocation Tests; Immunoglobulin E/blood; Methacholine Chloride/pharmacology; Prevalence; Respiratory; Hypersensitivity/blood/*epidemiology/immunology/physiopathology; Rhinitis/blood/*epidemiology/immunology/physiopathology; Risk Factors; Skin Tests
- BACKGROUND: Subjects with allergic rhinitis but no clinical evidence of asthma have greater bronchial hyperresponsiveness (BHR), and several factors have been implicated as its determinants. However, studies in young children are lacking. The aims of this study were to evaluate the prevalence of BHR in young children with allergic rhinitis and to investigate its risk factors. METHODS: Methacholine bronchial challenges were performed in 4- to 6-year-old nonasthmatic children with allergic rhinitis (n = 83) and in healthy nonatopic controls (n = 32), using a modified auscultation method. The end-point was defined as the appearance of wheezing and/or oxygen desaturation. Subjects were considered to have BHR when they had end-point concentrations of methacholine
- 0105-4538 (Print)
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