Publications
Detailed Information
Surgical resection of nodular ground-glass opacities without percutaneous needle aspiration or biopsy : 간유리 음영 결절에서 수술 전 조직검사가 필요한가에 대한 고찰
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 이춘택 | - |
dc.contributor.author | 조재영 | - |
dc.date.accessioned | 2017-07-19T10:31:43Z | - |
dc.date.available | 2017-07-19T10:31:43Z | - |
dc.date.issued | 2016-02 | - |
dc.identifier.other | 000000132503 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132819 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 의학과 내과학, 2016. 2. 이춘택. | - |
dc.description.abstract | Introduction: Percutaneous needle aspiration or biopsy (PCNA or PCNB) is an established diagnostic technique that has a high diagnostic yield. However, its role in the diagnosis of nodular ground-glass opacities (nGGOs) is controversial, and the necessity of preoperative histologic confirmation by PCNA or PCNB in nGGOs has not been well addressed.
Methods: We here evaluated the rates of malignancy and surgery-related complications, and the cost benefits of resecting nGGOs without prior tissue diagnosis when those nGGOs were highly suspected for malignancy based on their size, radiologic characteristics, and clinical courses. Patients who underwent surgical resection of nGGOs without preoperative tissue diagnosis from January 2009 to October 2013 were retrospectively analyzed. Results: Among 356 nGGOs of 324 patients, 330 (92.7%) nGGOs were resected without prior histologic confirmation. The rate of malignancy was 95.2% (314/330). In the multivariate analysis, larger size was found to be an independent predictor of malignancy (odds ratio, 1.086 | - |
dc.description.abstract | 95% confidence interval, 1.001-1.178, p =0.047). A total of 324 (98.2%) nGGOs were resected by video-assisted thoracoscopic surgery (VATS), and the rate of surgery-related complications was 6.7% (22/330). All 16 nGGOs diagnosed as benign nodules were resected by VATS, and only one patient experienced postoperative complications (prolonged air leak). Direct surgical resection without tissue diagnosis significantly reduced the total costs, hospital stay, and waiting time to surgery.
Conclusions: With careful selection of nGGOs that are highly suspicious for malignancy, surgical resection of nGGOs without tissue diagnosis is recommended as it reduces costs and hospital stay. | - |
dc.description.tableofcontents | Introduction 1
Material and Methods 5 Study population and study design 5 Radiologic evaluation 5 Total costs, days of hospitalization, and waiting time 7 Statistical analysis 8 Results 9 Patient characteristics 9 Radiologic characteristics 12 Surgical procedure and complications related to surgery 14 Pathologic diagnosis 14 Advantages on costs, hospital stay, and waiting time 16 Discussion 18 Conclusions 23 References 24 Abstract in Korean 31 | - |
dc.format | application/pdf | - |
dc.format.extent | 731580 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | Nodular ground-glass opacity | - |
dc.subject | Lung cancer | - |
dc.subject | Computed tomography | - |
dc.subject | Surgery | - |
dc.subject | Percutaneous needle aspiration or biopsy | - |
dc.subject.ddc | 610 | - |
dc.title | Surgical resection of nodular ground-glass opacities without percutaneous needle aspiration or biopsy | - |
dc.title.alternative | 간유리 음영 결절에서 수술 전 조직검사가 필요한가에 대한 고찰 | - |
dc.type | Thesis | - |
dc.contributor.AlternativeAuthor | Jaeyoung Cho | - |
dc.description.degree | Master | - |
dc.citation.pages | vi, 32 | - |
dc.contributor.affiliation | 의과대학 의학과 | - |
dc.date.awarded | 2016-02 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.