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MuSK antibody-positive, seronegative myasthenia gravis in Korea

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dc.contributor.authorLee, Jee-Young-
dc.contributor.authorSung, Jung Joon-
dc.contributor.authorCho, Joong-Yang-
dc.contributor.authorOh, Dong-Hoon-
dc.contributor.authorKim, Hyun-Jung-
dc.contributor.authorPark, Jong-Ha-
dc.contributor.authorLee, Kwang Woo-
dc.contributor.authorChoi, Young-Chul-
dc.contributor.authorVincent, Angela-
dc.date.accessioned2009-11-18T08:06:04Z-
dc.date.available2009-11-18T08:06:04Z-
dc.date.issued2006-03-21-
dc.identifier.citationJ Clin Neurosci. 2006 Apr;13(3):353-5. Epub 2006 Mar 20.en
dc.identifier.issn0967-5868 (Print)-
dc.identifier.urihttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WHP-4JHMXX2-7&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=13ad3a069651af3cf0ad687e4e737f69-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16546389-
dc.identifier.urihttps://hdl.handle.net/10371/13464-
dc.description.abstractSeveral reports from Western countries suggest differences in the clinical features of patients with muscle specific kinase (MuSK) antibody-positive and -negative seronegative myasthenia gravis (MG). We performed the first survey in Korea of MuSK antibodies, studying 23 patients with acetylcholine receptor (AChR)-antibody seronegative MG. MuSK antibodies were present in 4 (26.7%) of 15 generalized seronegative MG patients and none of 8 ocular seronegative MG patients. All four MuSK positive patients were females, with pharyngeal and respiratory muscle weakness, and required immunosuppressive treatment. However, overall disease severity and age at onset was similar to that of MuSK-negative MG and treatment responses were equally good.en
dc.language.isoen-
dc.publisherElsevieren
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAge of Onseten
dc.subjectAntibodies/*blooden
dc.subjectChilden
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImmunosuppressive Agents/pharmacologyen
dc.subjectInfanten
dc.subjectKorea/epidemiologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMyasthenia Gravis/*blood/*immunology/therapyen
dc.subjectReceptor Protein-Tyrosine Kinases/*immunologyen
dc.subjectReceptors, Cholinergic/*immunologyen
dc.subjectSeverity of Illness Indexen
dc.subjectThymectomy/methodsen
dc.titleMuSK antibody-positive, seronegative myasthenia gravis in Koreaen
dc.typeArticleen
dc.contributor.AlternativeAuthor이지영-
dc.contributor.AlternativeAuthor성정준-
dc.contributor.AlternativeAuthor조중양-
dc.contributor.AlternativeAuthor오동훈-
dc.contributor.AlternativeAuthor김현정-
dc.contributor.AlternativeAuthor박종하-
dc.contributor.AlternativeAuthor이광우-
dc.contributor.AlternativeAuthor최영철-
dc.identifier.doi10.1016/j.jocn.2005.04.028-
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