Rhodium-catalyzed reactions using alcohol as a carbon monoxide, nucleophile, hydration and alkylating source
로듐촉매를 사용하여 알코올을 일산화탄소와 친핵체, 수화 및 알킬화 공급원으로 이용하는 반응 연구
- 자연과학대학 화학부
- Issue Date
- 서울대학교 대학원
- rhodium; ester; alcohol; alkyne; carbonylation; chiral; α-alkylated ketone; hydration; alkylation; addition reaction
- 학위논문 (석사)-- 서울대학교 대학원 자연과학대학 화학부, 2017. 8. 정영근.
- A CO-gas-free rhodium-catalyzed alkoxycarbonylation of aryl iodide with alcohols has been developed. Alcohols, with/without the aid of an aldehyde, were used as a carbon monoxide and nucleophile source.
Moreover, atom economic rhodium-catalyzed synthesis of chiral α-alkylated ketone from alkyne with benzyl alcohols has been developed. Benzyl alcohols were used as a hydration and alkylation source.