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Optimal collimator rotation based on the outline of multiple brain targets in VMAT

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dc.contributor.authorKim, Jung-in-
dc.contributor.authorAhn, Beom Seok-
dc.contributor.authorChoi, Chang Heon-
dc.contributor.authorPark, Jong Min-
dc.contributor.authorPark, So-Yeon-
dc.date.accessioned2018-05-31T07:42:53Z-
dc.date.available2018-05-31T16:45:53Z-
dc.date.issued2018-05-09-
dc.identifier.citationRadiation Oncology, 13(1):88ko_KR
dc.identifier.issn1748-717X-
dc.identifier.urihttps://hdl.handle.net/10371/142663-
dc.description.abstractBackground
The aim of this study was to investigate the dosimetric quality in volumetric modulated arc therapy (VMAT) plans with optimal collimator angles that can represent the outline of multiple brain targets.

Methods
Twenty patients with multiple target volumes in the brain cases were selected retrospectively. To better represent the outline of the multiple brain targets, four conformal arc plans were generated for each patient using one full arc with four collimator settings. The optimal collimator angles calculated from the integrated multi-leaf collimator (MLC) aperture that had the smallest aperture size for certain collimator settings of the conformal arc plan were selected. VMAT plans with the optimal collimator angles with angular sections of 40° and 60° (Colli-VMAT (40°), Colli-VMAT (60°)) were generated, followed by evaluation of field sizes, dose-volumetric parameters and total monitor units (MUs).

Results
Patient-averaged values of field sizes for Colli-VMAT (40°) (111.5 cm2) were lowest and 1.3 times smaller than those for Std-VMAT (143.6 cm2). Colli-VMAT plans improved sparing of most normal organs but for brain stem and left parotid gland. For the total MUs, the averaged values obtained with the Colli-VMAT (40°) (390 ± 148 MU) were smaller than those obtained with the Std-VMAT (472 ± 235 MU).

Conclusions
The Colli-VMAT plans with smaller angular sections could be suitable in the clinic for multiple brain targets as well as for irregularly shaped targets. Determination of the optimal collimator rotation generally showed good normal tissue sparing and MU reduction for multiple brain targets.
ko_KR
dc.description.sponsorshipThis research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2017R1D1A1B03036093) and by a grant from the National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of
Korea (HA16C0025).
ko_KR
dc.language.isoenko_KR
dc.publisherBMCko_KR
dc.titleOptimal collimator rotation based on the outline of multiple brain targets in VMATko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor김정인-
dc.contributor.AlternativeAuthor안범석-
dc.contributor.AlternativeAuthor최창헌-
dc.contributor.AlternativeAuthor박종민-
dc.contributor.AlternativeAuthor박소연-
dc.identifier.doi10.1186/s13014-018-1039-5-
dc.language.rfc3066en-
dc.rights.holderThe Author(s).-
dc.date.updated2018-05-13T03:36:36Z-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Radiation Oncology (방사선종양학전공)Journal Papers (저널논문_방사선종양학전공)
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