Publications
Detailed Information
Secondary glioblastoma after treatment of intracranial germinoma - would radiation-only therapy still be safe? Case report
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwang, Kihwan | - |
dc.contributor.author | Lee, Kyu Sang | - |
dc.contributor.author | Choe, Gheeyoung | - |
dc.contributor.author | Cho, Byung-Gyu | - |
dc.contributor.author | Kim, Chae-Yong | - |
dc.date.accessioned | 2019-03-11T04:11:19Z | - |
dc.date.available | 2019-03-11T13:12:35Z | - |
dc.date.issued | 2018-11-16 | - |
dc.identifier.citation | BMC Cancer, 18(1):1119 | ko_KR |
dc.identifier.issn | 1471-2407 | - |
dc.identifier.uri | https://hdl.handle.net/10371/146926 | - |
dc.description.abstract | Back ground
Intracranial germinomas are one of the most radiosensitive tumors and are curable by radiotherapy (RT) alone. RT-only therapy without chemotherapy is effective. But, as patients with germinoma can expect long-term survival, the adverse effects of RT and late sequelae in survivors are of most concern. So, recently, standard treatment protocol of combination with chemotherapy and reduced dose of RT could be widely acceptable. Case presentation We report a patient with germinoma who developed RT-induced glioblastoma. He was diagnosed as biopsy-proven germinoma at the age of 12. Postoperatively, he underwent RT alone without chemotherapy and remained free of tumor without recurrence during long-term follow up. However, after almost 20 year, he developed RT-induced glioblastoma. Conclusions Although RT has the highest priority among treatments on intracranial germinomas, RT-only therapy with full dose for germinoma can have delayed severe complications. So, chemotherapy prior to reduced dose RT is more desirable. | ko_KR |
dc.description.sponsorship | None. | ko_KR |
dc.language.iso | en | ko_KR |
dc.subject | Germinoma | ko_KR |
dc.subject | Radiotherapy | ko_KR |
dc.subject | Secondary malignancy | ko_KR |
dc.subject | Glioblastoma | ko_KR |
dc.title | Secondary glioblastoma after treatment of intracranial germinoma - would radiation-only therapy still be safe? Case report | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 황기환 | - |
dc.contributor.AlternativeAuthor | 이규상 | - |
dc.contributor.AlternativeAuthor | 최기영 | - |
dc.contributor.AlternativeAuthor | 조병규 | - |
dc.contributor.AlternativeAuthor | 김채영 | - |
dc.identifier.doi | 10.1186/s12885-018-5073-3 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s). | - |
dc.date.updated | 2018-11-18T04:27:09Z | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.