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Bioresorbable Electronic Stent Integrated with Therapeutic Nanoparticles for Endovascular Diseases

DC Field Value Language
dc.contributor.authorSon, Donghee-
dc.contributor.authorLee, Jongha-
dc.contributor.authorLee, Dong Jun-
dc.contributor.authorGhaffari, Roozbeh-
dc.contributor.authorYun, Sumin-
dc.contributor.authorKim, Seok Joo-
dc.contributor.authorLee, Ji Eun-
dc.contributor.authorCho, Hye Rim-
dc.contributor.authorYoon, Soonho-
dc.contributor.authorYang, Shixuan-
dc.contributor.authorLee, Seunghyun-
dc.contributor.authorQiao, Shutao-
dc.contributor.authorLing, Daishun-
dc.contributor.authorShin, Sanghun-
dc.contributor.authorSong, Jun-Kyul-
dc.contributor.authorKim, Jaemin-
dc.contributor.authorKim, Taeho-
dc.contributor.authorLee, Hakyong-
dc.contributor.authorKim, Jonghoon-
dc.contributor.authorSoh, Min-
dc.contributor.authorLee, Nohyun-
dc.contributor.authorHwang, Cheol Seong-
dc.contributor.authorNam, Sangwook-
dc.contributor.authorLu, Nanshu-
dc.contributor.authorHyeon, Taeghwan-
dc.contributor.authorChoi, Seung Hong-
dc.contributor.authorKim, Dae-Hyeong-
dc.date.accessioned2020-02-17T04:29:34Z-
dc.date.available2020-02-17T04:29:34Z-
dc.date.created2018-06-27-
dc.date.created2018-06-27-
dc.date.created2018-06-27-
dc.date.issued2015-06-
dc.identifier.citationACS Nano, Vol.9 No.6, pp.5937-5946-
dc.identifier.issn1936-0851-
dc.identifier.other38040-
dc.identifier.urihttps://hdl.handle.net/10371/164330-
dc.description.abstractImplantable endovascular devices such as bare metal, drug eluting, and bioresorbable stents have transformed interventional care by providing continuous structural and mechanical support to many peripheral, neural, and coronary arteries affected by blockage. Although effective in achieving immediate restoration of blood flow, the long-term re-endothelialization and inflammation induced by mechanical stents are difficult to diagnose or treat. Here we present nanomaterial designs and integration strategies for the bioresorbable electronic stent with drug-infused functionalized nanoparticles to enable flow sensing, temperature monitoring, data storage, wireless power/data transmission, inflammation suppression, localized drug delivery, and hyperthermia therapy. In vivo and ex vivo animal experiments as well as in vitro cell studies demonstrate the previously unrecognized potential for bioresorbable electronic implants coupled with bioinert therapeutic nanoparticles in the endovascular system.-
dc.language영어-
dc.publisherAmerican Chemical Society-
dc.titleBioresorbable Electronic Stent Integrated with Therapeutic Nanoparticles for Endovascular Diseases-
dc.typeArticle-
dc.contributor.AlternativeAuthor최승홍-
dc.contributor.AlternativeAuthor김대형-
dc.contributor.AlternativeAuthor황철성-
dc.contributor.AlternativeAuthor현택환-
dc.contributor.AlternativeAuthor남상욱-
dc.identifier.doi10.1021/acsnano.5b00651-
dc.citation.journaltitleACS Nano-
dc.identifier.wosid000356988500034-
dc.identifier.scopusid2-s2.0-84935008696-
dc.citation.endpage5946-
dc.citation.number6-
dc.citation.startpage5937-
dc.citation.volume9-
dc.identifier.sci000356988500034-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorHwang, Cheol Seong-
dc.contributor.affiliatedAuthorNam, Sangwook-
dc.contributor.affiliatedAuthorHyeon, Taeghwan-
dc.contributor.affiliatedAuthorChoi, Seung Hong-
dc.contributor.affiliatedAuthorKim, Dae-Hyeong-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusCORONARY-ARTERY STENTS-
dc.subject.keywordPlusMESOPOROUS SILICA NANOPARTICLES-
dc.subject.keywordPlusCONTROLLED DRUG-DELIVERY-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusTHERANOSTIC APPLICATIONS-
dc.subject.keywordPlusPHOTOTHERMAL THERAPY-
dc.subject.keywordPlusORGANIC TRANSISTORS-
dc.subject.keywordPlusGOLD NANORODS-
dc.subject.keywordPlusSILK-
dc.subject.keywordPlusNANOCARRIERS-
dc.subject.keywordAuthorbioresorbable-
dc.subject.keywordAuthorstent-
dc.subject.keywordAuthortransient electronics-
dc.subject.keywordAuthorflexible electronics-
dc.subject.keywordAuthornanomedicine-
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  • School of Chemical and Biological Engineering
Research Area Chemistry, Materials Science

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