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Graves patient with thymic expression of thyrotropin receptors and dynamic changes in thymic hyperplasia proportional to graves disease activity

DC Field Value Language
dc.contributor.authorSong, Young Shin-
dc.contributor.authorWon, Jae-Kyung-
dc.contributor.authorKim, Mi Jeong-
dc.contributor.authorLee, Ji Hyun-
dc.contributor.authorKim, Dong-Wan-
dc.contributor.authorChung, June-Key-
dc.contributor.authorPark, Do Joon-
dc.contributor.authorPark, Young Joo-
dc.date.accessioned2020-04-27T11:13:25Z-
dc.date.available2020-04-27T11:13:25Z-
dc.date.created2018-08-28-
dc.date.issued2016-05-
dc.identifier.citationYonsei Medical Journal, Vol.57 No.3, pp.795-798-
dc.identifier.issn0513-5796-
dc.identifier.other47855-
dc.identifier.urihttps://hdl.handle.net/10371/165296-
dc.description.abstractThymic hyperplasia is frequently observed in Graves' disease. However, detectable massive enlargement of the thymus is rare, and the mechanism of its formation has remained elusive. This case showed dynamic changes in thymic hyperplasia on serial computed tomography images consistent with changes in serum thyrotropin receptor (TSH-R) antibodies and thyroid hormone levels. Furthermore, the patient's thymic tissues underwent immunohistochemical staining for TSH-R, which demonstrated the presence of thymic TSH-R. The correlation between serum TSH-R antibody levels and thymic hyperplasia sizes and the presence of TSH-R in her thymus suggest that TSH-R antibodies could have a pathogenic role in thymic hyperplasia.-
dc.language영어-
dc.publisher연세대학교의과대학-
dc.titleGraves patient with thymic expression of thyrotropin receptors and dynamic changes in thymic hyperplasia proportional to graves disease activity-
dc.typeArticle-
dc.contributor.AlternativeAuthor김동완-
dc.contributor.AlternativeAuthor박영주-
dc.contributor.AlternativeAuthor박도준-
dc.contributor.AlternativeAuthor정준기-
dc.identifier.doi10.3349/ymj.2016.57.3.795-
dc.citation.journaltitleYonsei Medical Journal-
dc.identifier.wosid000372578400036-
dc.identifier.scopusid2-s2.0-84961279120-
dc.citation.endpage798-
dc.citation.number3-
dc.citation.startpage795-
dc.citation.volume57-
dc.identifier.sci000372578400036-
dc.identifier.kciidART002102207-
dc.description.isOpenAccessY-
dc.contributor.affiliatedAuthorKim, Dong-Wan-
dc.contributor.affiliatedAuthorChung, June-Key-
dc.contributor.affiliatedAuthorPark, Do Joon-
dc.contributor.affiliatedAuthorPark, Young Joo-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusANTERIOR MEDIASTINAL MASS-
dc.subject.keywordPlusTHYROID-FUNCTION-
dc.subject.keywordPlusHYPERTHYROIDISM-
dc.subject.keywordAuthorThymus hyperplasia-
dc.subject.keywordAuthorgraves disease-
dc.subject.keywordAuthorreceptors thyrotropin-
dc.subject.keywordAuthorimmunoglobulins-
dc.subject.keywordAuthorthyroid-stimulating-
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