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Mesoporous silica-coated luminescent Eu3+ doped GdVO4 nanoparticles for multimodal imaging and drug delivery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Taeho | - |
dc.contributor.author | Lee, Nohyun | - |
dc.contributor.author | Park, Yong Il | - |
dc.contributor.author | Kim, Jangwon | - |
dc.contributor.author | Kim, Jaeyun | - |
dc.contributor.author | Lee, Eun Yeol | - |
dc.contributor.author | Yi, Minyoung | - |
dc.contributor.author | Kim, Bong-Geun | - |
dc.contributor.author | Hyeon, Taeghwan | - |
dc.contributor.author | Yu, Taekyung | - |
dc.contributor.author | Na, Hyon Bin | - |
dc.date.accessioned | 2020-04-27T13:43:16Z | - |
dc.date.available | 2020-04-27T13:43:16Z | - |
dc.date.created | 2020-03-17 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.citation | RSC Advances, Vol.4 No.86, pp.45687-45695 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.other | 92707 | - |
dc.identifier.uri | https://hdl.handle.net/10371/166085 | - |
dc.description.abstract | We describe a simple method for synthesizing mesoporous silica-coated luminescent europium-doped gadolinium vanadate (GdVO4:Eu3+@mSiO(2)) nanoparticles. Their biomedical applications as a potential imaging nanoprobe for both fluorescence imaging and magnetic resonance imaging (MRI) and as a simultaneous anti-cancer drug delivery vehicle are also discussed. Eu3+ doped GdVO4 nanoparticles exhibit strong red photoluminescence and the Gd3+ in GdVO4 can be used as a T-1 contrast agent for MRI. T-1-weighted MR contrast enhancement as well as sustained intracellular drug delivery can be achieved by the mesoporous silica layer coating onto a single nanoparticle. Enhanced T-1 MR contrast was proven by relaxometric studies on water access to the paramagnetic core. GdVO4:Eu3+@mSiO(2) nanoparticles as a new type of theragnostic (imaging and treatment) agent can provide new opportunities in a cancer treatment. | - |
dc.language | 영어 | - |
dc.publisher | Royal Society of Chemistry | - |
dc.title | Mesoporous silica-coated luminescent Eu3+ doped GdVO4 nanoparticles for multimodal imaging and drug delivery | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 현택환 | - |
dc.identifier.doi | 10.1039/c4ra06628f | - |
dc.citation.journaltitle | RSC Advances | - |
dc.identifier.wosid | 000342761600008 | - |
dc.identifier.scopusid | 2-s2.0-84907818351 | - |
dc.citation.endpage | 45695 | - |
dc.citation.number | 86 | - |
dc.citation.startpage | 45687 | - |
dc.citation.volume | 4 | - |
dc.identifier.sci | 000342761600008 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Hyeon, Taeghwan | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | MRI CONTRAST AGENTS | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE | - |
dc.subject.keywordPlus | OXIDE NANOPARTICLES | - |
dc.subject.keywordPlus | LANTHANIDE IONS | - |
dc.subject.keywordPlus | MANGANESE OXIDE | - |
dc.subject.keywordPlus | CANCER-THERAPY | - |
dc.subject.keywordPlus | QUANTUM DOTS | - |
dc.subject.keywordPlus | SHELL | - |
dc.subject.keywordPlus | NANOCRYSTALS | - |
dc.subject.keywordPlus | CONVERSION | - |
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