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Multifunctional silver-embedded magnetic nanoparticles as SERS nanoprobes and their applications
DC Field | Value | Language |
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dc.contributor.author | Jun, Bong-Hyun | - |
dc.contributor.author | Noh, Mi Suk | - |
dc.contributor.author | Kim, Jaeyun | - |
dc.contributor.author | Kim, Gunsung | - |
dc.contributor.author | Kang, Homan | - |
dc.contributor.author | Kim, Min-Soo | - |
dc.contributor.author | Seo, Young-Tae | - |
dc.contributor.author | Baek, Jongho | - |
dc.contributor.author | Kim, Jong-Ho | - |
dc.contributor.author | Park, Juyoung | - |
dc.contributor.author | Kim, Seongyong | - |
dc.contributor.author | Kim, Yong-Kweon | - |
dc.contributor.author | Hyeon, Taeghwan | - |
dc.contributor.author | Cho, Myung-Haing | - |
dc.contributor.author | Jeong, Dae Hong | - |
dc.contributor.author | Lee, Yoon-Sik | - |
dc.date.accessioned | 2020-04-29T08:07:41Z | - |
dc.date.available | 2020-04-29T08:07:41Z | - |
dc.date.created | 2020-03-18 | - |
dc.date.issued | 2010-01 | - |
dc.identifier.citation | Small, Vol.6 No.1, pp.119-125 | - |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.other | 92800 | - |
dc.identifier.uri | https://hdl.handle.net/10371/166249 | - |
dc.description.abstract | In this study, surface-enhanced Raman spectroscopy (SERS)-encoded magnetic nanoparticles (NPs) are prepared and utilized as a multifunctional tagging material for cancer-cell targeting and separation. First, silver-embedded magnetic NPs are prepared, composed of an 18-nm magnetic core and a 16-nm-thick silica shell with silver NPs formed on the surface. After simple aromatic compounds are adsorbed on the silver-embedded magnetic NPs, they are coated with. silica to provide them with chemical and physical stability. The resulting silica-encapsulated magnetic NPs (M-SERS dots) produce strong SERS signals and have magnetic properties. In a model application as a tagging material, the M-SERS dots are successfully utilized for targeting breast-cancer cells (SKBR3) and floating leukemia cells (SP2/O). The targeted cancer cells can be easily separated from the untargeted cells using an external magnetic field. The separated targeted cancer cells exhibit a Raman signal originating from the M-SERS dots. This system proves to be an efficient tool for separating targeted cells. Additionally, the magnetic-field-induced hot spots, which can provide a 1000-times-stronger SERS intensity due to aggregation of the NPs, are studied. | - |
dc.language | 영어 | - |
dc.publisher | Wiley - V C H Verlag GmbbH & Co. | - |
dc.title | Multifunctional silver-embedded magnetic nanoparticles as SERS nanoprobes and their applications | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 현택환 | - |
dc.contributor.AlternativeAuthor | 조명행 | - |
dc.identifier.doi | 10.1002/smll.200901459 | - |
dc.citation.journaltitle | Small | - |
dc.identifier.wosid | 000274036400019 | - |
dc.identifier.scopusid | 2-s2.0-73949092392 | - |
dc.citation.endpage | 125 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 119 | - |
dc.citation.volume | 6 | - |
dc.identifier.sci | 000274036400019 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Yong-Kweon | - |
dc.contributor.affiliatedAuthor | Hyeon, Taeghwan | - |
dc.contributor.affiliatedAuthor | Cho, Myung-Haing | - |
dc.contributor.affiliatedAuthor | Jeong, Dae Hong | - |
dc.contributor.affiliatedAuthor | Lee, Yoon-Sik | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | SURFACE-ENHANCED-RAMAN | - |
dc.subject.keywordPlus | ORGANIC-INORGANIC NANOPARTICLES | - |
dc.subject.keywordPlus | MULTIPLEX IMMUNOASSAY | - |
dc.subject.keywordPlus | SPECTROSCOPIC TAGS | - |
dc.subject.keywordPlus | QUANTUM DOTS | - |
dc.subject.keywordPlus | SCATTERING | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | BEADS | - |
dc.subject.keywordPlus | SIGNATURES | - |
dc.subject.keywordPlus | LABELS | - |
dc.subject.keywordAuthor | magnetic materials | - |
dc.subject.keywordAuthor | optically active materials | - |
dc.subject.keywordAuthor | silver nanoparticles | - |
dc.subject.keywordAuthor | surface-enhanced Raman scattering | - |
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