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The association of asthma and its subgroups with osteoporosis: a cross-sectional study using KoGES HEXA data
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wee, Jee Hye | - |
dc.contributor.author | Min, Chanyang | - |
dc.contributor.author | Park, Min Woo | - |
dc.contributor.author | Byun, Soo Hwan | - |
dc.contributor.author | Lee, Hyo-Jeong | - |
dc.contributor.author | Park, Bumjung | - |
dc.contributor.author | Choi, Hyo Geun | - |
dc.date.accessioned | 2020-10-14T06:12:56Z | - |
dc.date.available | 2020-10-14T15:16:04Z | - |
dc.date.issued | 2020-09-25 | - |
dc.identifier.citation | Allergy, Asthma & Clinical Immunology. 2020 Sep 25;16(1):84 | ko_KR |
dc.identifier.issn | 1710-1492 | - |
dc.identifier.uri | https://hdl.handle.net/10371/171072 | - |
dc.description.abstract | Background
A few studies have reported the association between asthma and osteoporosis. We aimed to analyze the association of asthma and its subgroups with osteoporosis in the Korean adult population. Methods We used the health examinee (HEXA) data from the Korean Genome and Epidemiology Study (KoGES) obtained between 2004 and 2016. We included 162,579 participants (n = 3,160 with asthma; n = 159,419 controls) who reported their previous histories of asthma and osteoporosis. The participants were categorized into 3 groups based on asthma management: participants who did not need further treatment due to controlled symptoms (well controlled); participants with ongoing treatment (being treated); participants who were not treated even though they had symptoms (not being treated). Multiple logistic regression analyses were used to calculate the adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for osteoporosis. Subgroup analyses for age and sex were conducted. Results The prevalence of osteoporosis was higher in patients with asthma (13.6%) than in controls (6.8%). In the full-adjusted model, the aORs for osteoporosis were 1.74 (95% CI 1.55–1.94, P < 0.001) in patients with asthma compared to controls. There were consistent findings across the age and sex subgroups. The aORs for osteoporosis were 1.43 (95% CI 1.10–1.86, P = 0.008) in the well-controlled asthma group; 1.55 (95% CI 1.28–1.89, P < 0.001) in the being treated asthma group; and 1.96 (95% CI 1.66–2.31, P < 0.001) in the not being treated asthma group compared to the control group. Conclusion Asthma was associated with osteoporosis in the Korean adult population. Patients with asthma not being treated showed the highest ORs for osteoporosis. | ko_KR |
dc.description.sponsorship | This research was funded by National Research Foundation (NRF) of Korea, grant number (NRF-2018-R1D1A1A0-2085328 by Hyo Geun Choi, NRF-2020R1G1A1005390 by Jee Hye Wee). The funding organization did not contribute to the design or conduct of this study, preparation, review, approval, or decision to submit this manuscript for publication. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Asthma | - |
dc.subject | Osteoporosis | - |
dc.subject | Chronic disease | - |
dc.subject | Epidemiology | - |
dc.title | The association of asthma and its subgroups with osteoporosis: a cross-sectional study using KoGES HEXA data | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 위지혜 | - |
dc.contributor.AlternativeAuthor | 민찬양 | - |
dc.contributor.AlternativeAuthor | 박민우 | - |
dc.contributor.AlternativeAuthor | 변수환 | - |
dc.contributor.AlternativeAuthor | 이효정 | - |
dc.contributor.AlternativeAuthor | 박범정 | - |
dc.contributor.AlternativeAuthor | 최효근 | - |
dc.identifier.doi | doi.org/10.1186/s13223-020-00482-6 | - |
dc.citation.journaltitle | Allergy, Asthma & Clinical Immunology | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2020-09-27T03:26:07Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 84 | ko_KR |
dc.citation.volume | 16 | ko_KR |
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