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Chemoradiotherapy for Extrahepatic Bile Duct Cancer with Gross Residual Disease after Surgery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Hae Jin | - |
dc.contributor.author | Kim, Kyubo | - |
dc.contributor.author | Chie, Eui Kyu | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.contributor.author | Kim, Sun Whe | - |
dc.contributor.author | Han, Sae-Won | - |
dc.contributor.author | Oh, Do-Youn | - |
dc.contributor.author | Im, Seock-Ah | - |
dc.contributor.author | Kim, Tae-You | - |
dc.contributor.author | Bang, Yung-Jue | - |
dc.contributor.author | Ha, Sung W. | - |
dc.date.accessioned | 2021-01-31T11:01:08Z | - |
dc.date.available | 2021-01-31T11:01:08Z | - |
dc.date.created | 2020-12-17 | - |
dc.date.created | 2020-12-17 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.citation | Anticancer Research, Vol.34 No.11, pp.6685-6690 | - |
dc.identifier.issn | 0250-7005 | - |
dc.identifier.other | 119266 | - |
dc.identifier.uri | https://hdl.handle.net/10371/172968 | - |
dc.description.abstract | Background: The purpose of the present study was to analyze the outcome of chemoradiotherapy for extrahepatic bile duct (EHBD) cancer patients with gross residual disease after surgical resection. Patients and Methods: We retrospectively analyzed 30 patients with EHBD adenocarcinoma who underwent chemoradiotherapy after palliative resection (R2 resection). Postoperative radiotherapy was delivered to the tumor bed including residual tumor and regional lymph nodes (range=40-55.8 Gy). Most patients underwent chemoradiotherapy concurrently with 5-fluorouracil (5-FU) or gemcitabine. Results: The 2-year locoregional progression-free, distant metastasis-free and overall survival rates were 33.3%, 42.4% and 44.5%, respectively. High radiation dose >= 50 Gy had a marginally significant impact on superior locoregional progression-free survival compared to 40 Gy (p=0.081). One patient developed grade 3 late gastrointestinal toxicity. Conclusion: Adjuvant chemoradiotherapy for EHBD cancer patients with gross residual disease after surgery was well-tolerated. There could be a chance for durable locoregional control and even long-term survival in selected patients. | - |
dc.language | 영어 | - |
dc.publisher | International Institute of Anticancer Research | - |
dc.title | Chemoradiotherapy for Extrahepatic Bile Duct Cancer with Gross Residual Disease after Surgery | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 임석아 | - |
dc.citation.journaltitle | Anticancer Research | - |
dc.identifier.wosid | 000344961300054 | - |
dc.identifier.scopusid | 2-s2.0-84916223198 | - |
dc.citation.endpage | 6690 | - |
dc.citation.number | 11 | - |
dc.citation.startpage | 6685 | - |
dc.citation.volume | 34 | - |
dc.identifier.sci | 000344961300054 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Chie, Eui Kyu | - |
dc.contributor.affiliatedAuthor | Jang, Jin-Young | - |
dc.contributor.affiliatedAuthor | Kim, Sun Whe | - |
dc.contributor.affiliatedAuthor | Oh, Do-Youn | - |
dc.contributor.affiliatedAuthor | Im, Seock-Ah | - |
dc.contributor.affiliatedAuthor | Kim, Tae-You | - |
dc.contributor.affiliatedAuthor | Bang, Yung-Jue | - |
dc.contributor.affiliatedAuthor | Ha, Sung W. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | EXTERNAL-BEAM RADIOTHERAPY | - |
dc.subject.keywordPlus | HILAR CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | PREOPERATIVE EVALUATION | - |
dc.subject.keywordPlus | MR CHOLANGIOPANCREATOGRAPHY | - |
dc.subject.keywordPlus | ADJUVANT RADIOTHERAPY | - |
dc.subject.keywordPlus | BRACHYTHERAPY | - |
dc.subject.keywordPlus | RESECTION | - |
dc.subject.keywordPlus | CHOLANGIOGRAPHY | - |
dc.subject.keywordPlus | EXPERIENCE | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordAuthor | Extrahepatic bile duct cancer | - |
dc.subject.keywordAuthor | chemoradiotherapy | - |
dc.subject.keywordAuthor | failure pattern | - |
dc.subject.keywordAuthor | R2 resection | - |
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