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Neoadjuvant chemotherapy followed by radiotherapy in epidermoid carcinoma of anus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chie, Eui Kyu | - |
dc.contributor.author | Wu, Hong Gyun | - |
dc.contributor.author | Heo, Dae Seog | - |
dc.contributor.author | Bang, Young-Jue | - |
dc.contributor.author | Kim, Noe Kyeong | - |
dc.contributor.author | Ha, Sung W. | - |
dc.date.accessioned | 2021-01-31T12:05:42Z | - |
dc.date.available | 2021-01-31T12:05:42Z | - |
dc.date.created | 2020-12-18 | - |
dc.date.issued | 2004-05 | - |
dc.identifier.citation | Tumori, Vol.90 No.3, pp.299-302 | - |
dc.identifier.issn | 0300-8916 | - |
dc.identifier.other | 119270 | - |
dc.identifier.uri | https://hdl.handle.net/10371/173269 | - |
dc.description.abstract | Aim and background: The purpose of this study was to analyze the efficacy of neoadjuvant fluorouracil-cisplatin chemotherapy combined with radiotherapy for anal cancer. Methods: Fourteen patients with epidermoid carcinoma of the anal canal were analyzed. Treatment consisted of three cycles of 5-fluorouracil (1000 mg/m(2) bolus on days 1-5) and cisplatin (60 mg/m(2) bolus on day 1) followed by 50.4 Gy to the pelvis and perineum over 5.5 weeks. Both inguinal lymphatics were irradiated with an identical dose schedule. The median follow-up was 78 months. Results: Five-year overall survival rate and sphincter preservation rate was 85.1% and 85.7%, respectively. Response to chemoradiotherapy was the only significant factor with univariate analysis (P = 0.031). There were no complications of RTOG grade 3 or higher. Conclusions: Neoadjuvant chemotherapy with a cisplatin-based regimen rather than concurrent regimen plus radiotherapy may decrease complications without compromising survival or sphincter preservation. | - |
dc.language | 영어 | - |
dc.publisher | II Pensiero Scientifico Editore srl | - |
dc.title | Neoadjuvant chemotherapy followed by radiotherapy in epidermoid carcinoma of anus | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 방영주 | - |
dc.identifier.doi | 10.1177/030089160409000307 | - |
dc.citation.journaltitle | Tumori | - |
dc.identifier.wosid | 000223049000007 | - |
dc.identifier.scopusid | 2-s2.0-3242742191 | - |
dc.citation.endpage | 302 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 299 | - |
dc.citation.volume | 90 | - |
dc.identifier.sci | 000223049000007 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Chie, Eui Kyu | - |
dc.contributor.affiliatedAuthor | Wu, Hong Gyun | - |
dc.contributor.affiliatedAuthor | Heo, Dae Seog | - |
dc.contributor.affiliatedAuthor | Bang, Young-Jue | - |
dc.contributor.affiliatedAuthor | Kim, Noe Kyeong | - |
dc.contributor.affiliatedAuthor | Ha, Sung W. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DOSE RADIATION-THERAPY | - |
dc.subject.keywordPlus | ANAL-CANAL CANCER | - |
dc.subject.keywordPlus | RANDOMIZED TRIAL | - |
dc.subject.keywordPlus | PHASE-II | - |
dc.subject.keywordPlus | 5-FLUOROURACIL | - |
dc.subject.keywordPlus | FLUOROURACIL | - |
dc.subject.keywordPlus | CHEMORADIATION | - |
dc.subject.keywordPlus | CISPLATIN | - |
dc.subject.keywordPlus | MITOMYCIN | - |
dc.subject.keywordAuthor | anal cancer | - |
dc.subject.keywordAuthor | neoadjuvant chemotherapy | - |
dc.subject.keywordAuthor | radiotherapy | - |
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