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The R principles in laboratory animal experiments

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dc.contributor.authorLee, Kook Hyun-
dc.contributor.authorLee, Dong Won-
dc.contributor.authorKang, Byeong Chul-
dc.date.accessioned2021-03-23T04:36:19Z-
dc.date.available2021-03-23T13:38:01Z-
dc.date.issued2020-12-09-
dc.identifier.citationLaboratory Animal Research. 2020 Dec 09;36(1):45ko_KR
dc.identifier.issn2233-7660-
dc.identifier.urihttps://hdl.handle.net/10371/173892-
dc.description.abstractSince the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal experiments are performed by the Three Rs concept, animal researches which do not comply with international rules and standards are not accepted as well. As animal welfare has been important global issues, the methods to assess animal welfare compromise and distress have been proposed. Humanity is accepted as the goal of the Three Rs, however, another fourth R, Refusal of fruitless protocol or Responsibility for the experimental animal and social, scientific status of the animal experiments has been proposed. After establishing goals of animal research in a respective society, reliable knowledge can be obtained while improving laboratory animal welfare.ko_KR
dc.description.sponsorshipThis report was supported by 0620062449 fund of Seoul National University Hospital.ko_KR
dc.language.isoenko_KR
dc.publisherBMCko_KR
dc.subjectReplacement-
dc.subjectReduction-
dc.subjectRefinement-
dc.subjectResponsibility-
dc.subjectRefusal-
dc.subjectWelfare-
dc.titleThe R principles in laboratory animal experimentsko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor이국현-
dc.contributor.AlternativeAuthor이동원-
dc.contributor.AlternativeAuthor강병철-
dc.identifier.doi10.1186/s42826-020-00078-6-
dc.citation.journaltitleLaboratory Animal Researchko_KR
dc.language.rfc3066en-
dc.rights.holderThe Author(s)-
dc.date.updated2021-01-27T10:46:21Z-
dc.citation.number1ko_KR
dc.citation.startpage45ko_KR
dc.citation.volume36ko_KR
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