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Current advances of epigenetics in periodontology from ENCODE project: a review and future perspectives
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Young-Dan | - |
dc.contributor.author | Kim, Woo-Jin | - |
dc.contributor.author | Ryoo, Hyun-Mo | - |
dc.contributor.author | Kim, Hong-Gee | - |
dc.contributor.author | Kim, Kyoung-Hwa | - |
dc.contributor.author | Ku, Young | - |
dc.contributor.author | Seol, Yang-Jo | - |
dc.date.accessioned | 2021-07-13T07:21:10Z | - |
dc.date.available | 2021-07-13T16:22:57Z | - |
dc.date.issued | 2021-04-26 | - |
dc.identifier.citation | Clinical Epigenetics. 2021 Apr 26;13(1):92 | ko_KR |
dc.identifier.issn | 1868-7083 | - |
dc.identifier.uri | https://hdl.handle.net/10371/174685 | - |
dc.description.abstract | Background
The Encyclopedia of DNA Elements (ENCODE) project has advanced our knowledge of the functional elements in the genome and epigenome. The aim of this article was to provide the comprehension about current research trends from ENCODE project and establish the link between epigenetics and periodontal diseases based on epigenome studies and seek the future direction. Main body Global epigenome research projects have emphasized the importance of epigenetic research for understanding human health and disease, and current international consortia show an improved interest in the importance of oral health with systemic health. The epigenetic studies in dental field have been mainly conducted in periodontology and have focused on DNA methylation analysis. Advances in sequencing technology have broadened the target for epigenetic studies from specific genes to genome-wide analyses. Conclusions In line with global research trends, further extended and advanced epigenetic studies would provide crucial information for the realization of comprehensive dental medicine and expand the scope of ongoing large-scale research projects. | ko_KR |
dc.description.sponsorship | This research was supported by Grants from MSIP/IITP (2017-0-00398) and Basic Science Research Program (2016R1A1A3A04004838/2020R1 C1C1005830) through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Chronic disease | - |
dc.subject | Epigenetics | - |
dc.subject | ENCODE project | - |
dc.subject | Next-generation sequencing | - |
dc.subject | Periodontology | - |
dc.subject | Personalized medicine | - |
dc.title | Current advances of epigenetics in periodontology from ENCODE project: a review and future perspectives | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 조영단 | - |
dc.contributor.AlternativeAuthor | 김우진 | - |
dc.contributor.AlternativeAuthor | 유현모 | - |
dc.contributor.AlternativeAuthor | 김홍기 | - |
dc.contributor.AlternativeAuthor | 김경화 | - |
dc.contributor.AlternativeAuthor | 구영 | - |
dc.contributor.AlternativeAuthor | 설양조 | - |
dc.identifier.doi | 10.1186/s13148-021-01074-w | - |
dc.citation.journaltitle | Clinical Epigenetics | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-05-02T03:07:54Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 92 | ko_KR |
dc.citation.volume | 13 | ko_KR |
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