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Adverse reaction to Coartem (artemether/lumefantrine) resulting in oculogyric crisis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Amponsah, Emmanuel K. | - |
dc.contributor.author | Sodnom-Ish, Buyanbileg | - |
dc.contributor.author | Anyetei-Anum, Aaron S. | - |
dc.contributor.author | Frimpong, Paul | - |
dc.contributor.author | Kim, Soung Min | - |
dc.date.accessioned | 2021-07-30T00:54:58Z | - |
dc.date.available | 2021-07-30T09:56:07Z | - |
dc.date.issued | 2021-05-17 | - |
dc.identifier.citation | Maxillofacial Plastic and Reconstructive Surgery. 2021 May 17;43(1):13 | ko_KR |
dc.identifier.issn | 2288-8586 | - |
dc.identifier.uri | https://hdl.handle.net/10371/174771 | - |
dc.description.abstract | Background
Artemether/lumefantrine (AL), sold under the brand name Coartem, is the most common artemisinin-based combination therapy for the treatment of malaria. Drug-induced oculogyric crisis is a neurological disorder characterized by frequent upward deviations of the eye. In the literature, no cases of Coartem-induced oculogyric crisis have been reported in Ghana. Case presentation A 19-year-old male patient, who presented fever measuring 37.9 °C, general body pains, and weakness was prescribed with antimalarial therapy artemether/lumefantrine, Coartem®, from a local pharmacy. Just after initiation of treatment, the patient complained of double vision, involuntary upward eye deviation, and inability to close both eyes. The patient was diagnosed with Coartem-induced oculogyric crisis and was treated with the cessation of the causing agent and intramuscular injection of promethazine hydrochloride. Conclusions When a patient exhibits a neurological disorder, such as oculogyric crisis, with normal conscious state and normal vital signs, special attention should be given to obtaining a history of recently administered medications. Clinicians should recognize adverse reactions to drugs based on a thorough patient history and examination. The goal of this report was to present Coartem-induced oculogyric crisis. | ko_KR |
dc.description.sponsorship | This research was supported by Basic Science Research Program funded by the Ministry of Education (2017R1D1A1B04029339) and by grant no 03-2019-0043 from the SNUDH Research Fund. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | Springer Open | ko_KR |
dc.subject | Antimalarial | - |
dc.subject | Artemether-lumefantrine | - |
dc.subject | Rapid diagnostic test | - |
dc.subject | Oculogyric crisis | - |
dc.subject | Dystonic reactions | - |
dc.title | Adverse reaction to Coartem (artemether/lumefantrine) resulting in oculogyric crisis | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김성민 | - |
dc.identifier.doi | 10.1186/s40902-021-00300-y | - |
dc.citation.journaltitle | Maxillofacial Plastic and Reconstructive Surgery | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-05-23T03:17:06Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 13 | ko_KR |
dc.citation.volume | 43 | ko_KR |
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